نتایج جستجو برای: esophageal squamous cell carcinoma
تعداد نتایج: 1917383 فیلتر نتایج به سال:
PURPOSE To analyze the epidemiological features of patients with esophageal cancer according to the histopathological types: squamous cell carcinoma or adenocarcinoma. METHODS A total of 100 patients with esophageal cancer, being 50 squamous cell carcinomas and 50 adenocarcinomas were analyzed for demographics, nutritional factors, lifestyle habits, benign pathological conditions associated, ...
BACKGROUND Esophageal carcinosarcoma is a very rare neoplasm and its clinicopathological characteristics and the prognostic factors that influence the clinical outcome of the patient remain a matter of controversy. PATIENTS AND METHODS Twenty patients with esophageal carcinosarcoma were referred to our institutions. Tissue blocks were reviewed and sections containing both carcinomatous and sa...
Hypoxia inducible factor 1α (HIF-1α) is highly expressed and is implicated in the progression of esophageal squamous cell carcinoma. To investigate the potential mechanism by which HIF-1α contributes to the progression of esophageal squamous cell carcinoma, here we established stable esophageal carcinoma cell lines Eca-109 and TE- 13 in which HIF-1α was depleted by shRNA mediated gene silencing...
Fas (APO-1/CD95) is a cell surface receptor that mediates apoptosis when it reacts with Fas ligand (FasL) or Fas antibody. In this study, we analyzed Fas and FasL expression in normal esophageal mucosa and esophageal squamous cell carcinomas. Reverse transcriptase-PCR revealed that Fas, soluble Fas, and FasL were expressed in all eight esophageal squamous carcinoma cell lines analyzed. Furtherm...
most patients with gastrointestinal cancers refer to the health centers at advanced stages of the disease and conventional treatments are not significantly effective for these patients. therefore, using modern therapeutic approaches with lower toxicity bring higher chance for successful treatment and reduced adverse effects in such patients. the aim of this study is to evaluate the effect of av...
Objective(s): Epigenetic regulation of gene expression can be carried out through chromatin remodeling enzymes such as SWI/SNF. Brg1 also known as SMARCA4 is a catalytic subunit of SWI/SNF, which is necessary for MMPs expression. Matrix metalloproteinases (MMPs) are known as important player enzymes during tumor progression and metastasis. Aberrant epigenetic modification of chromatin should be...
Introduction: Despite the high incidence of esophageal and thymic carcinoma in human being, co-existence of these two malignant lesions is very rare. In this study we have reported an 81 year old man with a huge mediastinal tumor (Thymoma) and Squamous Cell Carcinoma (SCC) of esophagus. Case report: An 81 year old man presented with hiccups and progressive dysphagia for solids and was admit...
in this archival analysis of genetic & protein alterations in the p53 tumor suppressor gene, we used immunohistochemical methods for detection of these alterations. the tumor series includes: 61 paraffin embedded esophageal squamous cell carcinoma from a high incidence (ethnic) & a non-high incidence regions in iran.
skin cancer is one of the most important type of cancers in the world. in this way, molecular investigation in order to detect some novel mechanisms and polymorphisms involved in cancer development can be impressive and vital. in this way, the aim of this study was the histopathological investigation of skin cancer and its relationship with polymorphism of cdkn2a gene. this case-control study w...
a primary intraosseous carcinoma (pioc) is a squamous cell carcinoma arising within the jawbone andshould be differentiated from a malignant ameloblastoma. it is not due to arising from an odontogenic cyst or tumor. the possibility of the lesion being a metastasis fromanotherprimary site should be considered, and excluded by a careful history and examination. the diagnosis of a pioc is rare...
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