OBJECTIVE During puberty, the hypothalamus-pituitary-gonadal (HPG) axis is activated, leading to increases in luteinizing hormone (LH), follicle stimulating hormone (FSH) and sex steroids (testosterone and estradiol) levels. We aimed to study the association between hypothalamic and pituitary volumes and development of pubertal hormones in healthy pubertal children. METHOD Hormone levels of L...

Estrogens are a family of female sexual hormones with an exceptionally wide spectrum of effects. When rats and mice are used in estrogen research they are commonly ovariectomized in order to ablate the rapidly cycling hormone production, replacing the 17β-estradiol exogenously. There is, however, lack of consensus regarding how the hormone should be administered to obtain physiological serum co...

Following the isolation of estrone from the urine of pregnant women by Doisy, Veler, and Thayer (I), by Butenandt (2), and by Laqueur, Dingemanse, and Kober (3), this ketonic estrogen was considered to be the hormone of the ovarian follicle. In 1936, however, MacCorquodale, Thayer, and Doisy (4) identified ar-estradiol as the principal estrogenic hormone of the liquor folliculi of the sow ovary...

introduction: the aim of this study was to evaluate the correlation between serum levels of ovarian and gonadotropin hormones, age and number of follicles with follicular alkaline and acid phosphatase activity in infertile women under controlled ovarian hyperstimulation. methods: after collection of follicular fluid and calculation of the number of follicles, the specific activity of alkaline (...

The goal of the present study was to explore the effects of long-term hormone deprivation on the ability of subsequent estrogen replacement to affect cognition. Female rats, 12 months of age, underwent ovariectomies (n = 30) or sham surgeries (n = 10). Intact rats and 20 ovariectomized rats received cholesterol implants. Ten ovariectomized rats received implants containing 25% estradiol. Five m...

Abstract Background Sex hormones may be associated with a higher incidence of ischemic stroke or stroke-related events. In observational studies, lower testosterone concentrations are infirmity, vascular disease, and adverse cardiovascular risk factors. Currently, female sexual considered neuroprotective agents. The purpose this study was to assess the role sex ratio estradiol/testosterone (E/T...

there is a challenging debate on the effect of premature luteinization on the clinical outcome of ‘controlled ovarian hyperstimulation' (coh) using long ‘gonadotropin-releasing hormone agonist' (gnrha) cycles. premature luteinization is defined as late follicular progesterone/estradiol ratio more than 1 on the day of human chorionic gonadotropin (hcg) administration. we carried out a retrospect...

The renal sexual segment (RSS) of immature Northern and Diamondback Water Snakes and Red-Sided Garter Snakes exhibited varying responses to testosterone or 17beta-estradiol. In both male and female water snakes, kidney mass was not a reliable indicator of hormone treatment, whereas tubule diameter, epithelial height and number of sexual granules responded to hormone treatment. In male water sna...

Objective(s):Estrogen is a sexual hormone that has prominent effects on reproductive and non-reproductive tissues. The aim of this study is to evaluate the effects of estrogen on the proliferation and neural differentiation of human adipose derived stem cells (ADSCs) during neurogenic differentiation. Materials and Methods: Isolated human ADSCs were trans-differentiated in neural induction med...