Recent reports indicate that SAhRMs such as 3, 3’-diindolylmethane (DIM) inhibit α-estrogen receptor (ER) expression and estrogen signaling in human breast cancer cells and inhibit androgen receptor (AR) signaling in human prostate cancer cells. DIM is an AhR agonist derived from Brassica vegetables and has been shown to have antiproliferative and proapoptotic effects in breast and prostate can...
