Here we present the case of a patient affected with a unique association of Sweet's syndrome, idiopathic myelofibrosis, spindle-cell thymoma, myasthenia gravis and Good's syndrome (a rare form of thymoma-related, combined immunodeficiency presenting with recurrent respiratory infections). Conventional therapies (corticosteroids, colchicine, DDS, clofazimine) were ineffective or were contraindic...

Retinoids are of particular interest in experimental and clinical oncology. They exert their antitumor activity through inhibition of cell proliferation, induction of cell differentiation, suppression of oncogene expression and inhibition of angiogenesis. In animal experiments, retinoids have preventive and therapeutic effects on premalignant and malignant lesions. Clinically, chemoprevention w...

Epidermolytic hyperkeratosis is a form of ichthyosis normally resistant to topical treatments. Female patient monitored since 1978 diagnosed with epidermolytic hyperkeratosis. Clinical examination showed generalized hyperkeratosis and scaling. Given that no other treatments were available at the time, the patient was initially treated with keratolytic, systemic vitamin A and moisturizers, with ...

Various treatment of papillomatosis in dogs have been described: oral azithromycin [33], cimetidine [6], etretinate [22] and human recombinant interferon-α 2a [27], intramuscular Propionibacterium acnes [21], intravenous taurolidine [3], subcutaneous live papillomavirus vaccine [4], topical applications of 5-fluorouracil or imiquimod and surgical excision, crushing laser surgery or cryosurgical...

Acne inversa has to be differentiated from furuncles, carbuncles, vegetating pyoderma, cutaneous tuberculosis, actinomycosis, lymphogranuloma inguinale and Crohn’s disease.[5] Treatment options include antiseptics, antibiotics and corticosteroids.[6] Tetracycline, clindamycin or rifampicin have all been tried with limited success. Isotretinoin is effective in some cases only. Etretinate and aci...