Objective Improvement in ex vivo lung perfusion protocols could increase the number of donors available for transplantation and protect lungs from primary graft dysfunction. We hypothesize that perfusate adsorption during reconditions allograft to ischemia–reperfusion injury after transplantation. Methods Donor pig were preserved 24 hours at 4°C, followed by 6 according Toronto protocol. The wa...

Lung transplantation offers a lifesaving therapy for patients with end-stage lung disease but its availability is presently limited by low organ utilization rates donor lungs frequently excluded due to unsuitability at assessment. When does occur, recipients are then vulnerable primary graft dysfunction (PGD), multitudinous short-term complications, and chronic allograft dysfunction. The decisi...

Lung transplantation has come to be viewed as the best treatment option for various end-stage lung diseases. The low number of viable donors continues to be a major obstacle to increasing the number of lung transplants, resulting in high mortality among patients on the waiting list. Unlike transplantation of other solid organs, lung transplantation is primarily limited not by the absolute numbe...

Lung transplantation has come to be viewed as the best treatment option for various end-stage lung diseases. The low number of viable donors continues to be a major obstacle to increasing the number of lung transplants, resulting in high mortality among patients on the waiting list. Unlike transplantation of other solid organs, lung transplantation is primarily limited not by the absolute numbe...