Activation of Cdc14 phosphatase, controlled by a signalling cascade known as the mitotic exit network, is the final switch that drives cells from mitosis into the next cell cycle. The recent discovery of a novel network that regulates early Cdc14 activation has revealed the unexpected existence of a two-step control of mitotic exit.

This study examines a drunk driving population sentenced to a Day Reporting Center in a southwestern Indiana county from January 2002 through December 2003._ Specifically, using crosstqbulations and chi-square analyses, this study concentrates on the "exit status" and "post-program recidivism" among those participants._The results of this study suggest that placing convicted drink drivers in a ...

We studied the Einstein-Brans-Dicke cosmology in detail. The difference of the evolution of the universe is significant between Einstein-Brans-Dicke cosmology and standard big-bang model during the radiation-dominated era. The power-law evolution of the scale factor is fast enough to solve the cosmological puzzles and slow enough to avoid the graceful exit problem. However, the constraints from...

String cosmology solutions are examined in a generalized phase-space including sources representing arbitrary corrections to lowest order string-dilatongravity effective action. We find a set of necessary conditions for a graceful exit transition from a dilaton-driven inflationary phase to a radiation dominated era. We show that sources allowing such a transition have to violate energy conditio...

Firms can motivate workers by offering them social status. Much of the literature argues that a rise in status is a powerful work incentive while ignoring its impact on coordination. However, when workers need to collaborate while having individual vested interests, too large a difference in status distorts how workers coordinate, i.e., one worker compromises too much with respect to his most p...

In contrast to x-rays, protons have a low entrance dose, a well-defined high-dose plateau (“Bragg peak”), and no exit dose beyond the target tissue. These properties make them ideal for treating localized cancers in areas surrounded by doselimiting normal structures. Their routine use required the creation of dedicated medical treatment centers which have only been in existence since the early ...

The determination of the dose delivered to the body during Total Body Irradiation (TBI) is not easy, as direct measurements are impossible. This article presents the intention to develop a systematic and simple method for absorbed dose determination in(60)Co TBI using mid plane dose factors (MDF) and external measurements, i.e. entrance and exit dose readings by semiconductor detectors. In orde...

Further, even though it is intellectually accepted that we have methodological means to combat these factors and provide benefits during the evolutionary process, development managers still choose short term goals over these long term benefits. Given a choice between getting a system out as early as possible and doing a proper design that will evolve gracefully, the first is invariably chosen a...