نتایج جستجو برای: expanded disability status scale
تعداد نتایج: 1069993 فیلتر نتایج به سال:
OBJECTIVE To investigate the value of Expanded Disability Status Scale (EDSS) worsening sustained for at least 6 months and other parameters as predictors for disability status. DESIGN Retrospective analysis of the Multiple Sclerosis Collaborative Research Group study data. SETTING The intramuscular interferon beta-1a pivotal trial was a double-blind, placebo-controlled phase 3 study. PAR...
The objective of this study was to test a new version of the Magnetic Resonance Disease Severity Scale (MRDSS2), incorporating cerebral gray matter (GM) and spinal cord involvement from 3 T MRI, in modeling the relationship between MRI and physical disability or cognitive status in multiple sclerosis (MS). Fifty-five MS patients and 30 normal controls underwent high-resolution 3 T MRI. The pati...
OBJECTIVES To evaluate long term change in impairment, disability, and health related functional status in patients with severe spasticity who received intrathecal baclofen. METHODS A long term (more than five years) observational longitudinal follow up study assessing 21 patients who received intrathecal baclofen given by programmable pump. Patients had chronic disabling spasticity which did...
Aim. The aim of the study was to investigate persons with dementia (PwD) and their informal caregiver’s experiences of intersectorial information, communication and collaboration throughout the trajectory of dementia care in eight European countries. Design. Focus groups were applied in eight European countries; Estonia (EE), Finland (FI), France (FR), Germany (DE), The Netherlands (NL), Spain ...
Objective To perform a meta-analysis of randomized, blinded, multiple sclerosis (MS) clinical trials, to test the hypothesis that efficacy of immunomodulatory disease-modifying therapies (DMTs) on MS disability progression is strongly dependent on age. Methods We performed a literature search with pre-defined criteria and extracted relevant features from 38 clinical trials that assessed effic...
BACKGROUND Much research has gone into the assessment of function and health-related quality of life (HRQOL) in those with multiple sclerosis (MS). The Medical Outcomes Study 36-item short form (SF-36) has been widely used in this population but current recommendations are that it be supplemented with condition-specific measures such as the MS Quality of Life Inventory (MSQLI) and the MS Functi...
patients and methods in this study, a total of 92 patients with relapsing-remitting multiple sclerosis (rrms) were randomly allocated into three equal groups; each treatment group received one of the foregoing drugs (cinnovexr, rebif and betaferon) for one year. at the beginning and end of the study, patients ‘ edss was measured and compared. results in this study, the relative frequency of fem...
OBJECTIVES To assess differences in magnetisation transfer ratio (MTR) analysis of normal appearing white matter (NAWM) in patients with familial multiple sclerosis (MS) and those with sporadic MS. METHODS 10 patients with familial MS, 10 patients with sporadic MS, and 10 healthy subjects were included in the study. Groups were matched according to the sex, age, disease duration, type of dise...
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