Despite intensive study of p53, the regulation of p53 cellular localization is still poorly understood. This is an overview of the elements and molecules involved in p53 nucleocytoplasmic transportation. These include the nuclear import and export signals of p53, inhibition of p53 nuclear import and export by oligomerization, MDM2-mediated p53 nuclear export, and possible roles of p53 phosphory...

AIMS During cardiac hypertrophy, cardiomyocytes (CMs) increase in the size and expression of cytoskeletal proteins while reactivating a foetal gene programme. The process is proposed to be dependent on increased nuclear export and, since nuclear pore trafficking has limited capacity, a linked decrease in import. Our objective was to investigate the role of nuclear import and export in control o...

Effects of increasing sink-source ratio on rate of translocation and net carbon exchange were studied by darkening all but one source leaf of Beta vulgaris L. or one primary leaf of Phaseolus vulgaris L. Rates of export of labeled material and patterns of its distribution among sinks were studied by means of GM detectors. Changes in export and import rates were compared with adjustments in star...

We examine the importance of a firm‟s R and D activity, technology import and intra-sectoral R and D spillovers on the decision to export and export intensity using firm level panel data for the Indian automobile sector from 2000-2014. R and D and technology import activities are found to be important determinants of export activity. There is evidence that R and D spillovers exert positive effe...

Nuclear transport is an energy-dependent process mediated by saturable receptors. Import and export receptors are thought to recognize and bind to nuclear localization signals or nuclear export signals, respectively, in the transported molecules. The receptor-substrate interaction can be direct or mediated by an additional adapter protein. The transport receptors dock their cargoes to the nucle...

Cytochrome b2 reaches the intermembrane space of mitochondria by transport into the matrix followed by export across the inner membrane. While in the matrix, the protein interacts with hsp60, which arrests its folding prior to export. The bacterial-type export sequence in pre-cytochrome b2 functions by inhibiting the ATP-dependent release of the protein from hsp60. Release for export apparently...

In this study, China’s virtual water trade was measured on the basis of multi-region input/output tables, and its influencing factors change were decomposed. The results revealed that export import increased from 161.5 billion tons 114.07 in 2007 to 193.31 157.1 2014, respectively. Eight economies accounted for more than 50% total import, whereby United States, Japan, Europe reached 44% (export...

This study aims to examine the effect of trade between Indonesia and Egypt on Indonesia's economic growth in view Islamic economics. The research uses a quantitative approach with multiple linear regression equipped export-import data from Ministry Trade BPS 2017-2022. results are partially Indonesian export variable has negative significant effect, import positive growth. As well as simultaneo...

The level of price volatility should theoretically be confined to export parity price levels at the lower end and import parity price levels at the upper end of the price band, reflecting supply and demand conditions during surplus and deficit marketing seasons respectively. A greater gap between these export and import parity prices will reflect high marketing costs, often representing high tr...