Senescence is a genetically regulated oxidative process that involves a general degradation of cellular structures and enzymes and the mobilization of the products of degradation to other parts of the plant. The cDNA-AFLP (cDNA-Amplified Fragment Length Polymorphism) analysis has been used under stringent PCR conditions afforded by ligation of adapters to restriction fragments, and the use of s...

• differential gene expression using mRNA chips – diabetes and obesity study (biochemistry) • lean vs. obese mice: how do they differ? • what is the role of genetic background? – detecting genes at low expression levels • inference issues – formal evaluation of each gene with(out) replication • smoothly combine information across genes – significance level and multiple comparisons – general pat...

Medical research would benefit from automatic methods that support eligibility evaluation for patient enrollment in clinical trials and design of eligibility criteria. In this study we addressed the problem of formalizing eligibility criteria. By analyzing a large set of breast cancer clinical trials we derived a set of patterns, that capture typical structure of conditions, pertaining to synta...

We introduce parameterized pattern queries as a new paradigm to extend traditional pattern expressions over sequence databases. A parameterized pattern is essentially a string made of constant symbols or variables where variables can be matched against any symbol of the input string. Parameterized patterns allow a concise and expressive definition of regular expressions that would be very compl...

background: the up-regulation of galectin-3, galectin-9, and galectin-15 expression in the luminal and glandular epithelium was reported in preparation of the endometrium for embryo implantation at the midlutheal phase. however, no data was available regarding the expression and the distribution pattern of galectin-8 in the human endometrium during a regular menstrual cycle. objective: the curr...