As long as the aetiology ofulcerative colitis remains obscure, treatment of the disease must be confined to symptomatic relief measures. A wide variety of both medical and surgical methods of treatment have been tried over the years. During the past decade, our interest and expectations have been focused mainly on two principles of treatment, one medical and one surgical. The introduction of st...

Two main hereditary colorectal cancer syndromes have been described, namely familial adenomatous polyposis coli (FAP) and hereditary non-polyposis colorectal cancer (HNPCC). FAP is a disease characterised by autosomal dominant inheritance where the affected subjects develop hundreds to thousands of adenomatous polyps throughout the whole colon, usually during their teenage years. This syndrome ...

An important issue in the management of inflammatory bowel disease (IBD) is the risk for lymphatic or extracolonic malignancies reported in patients receiving prolonged immunosuppressive therapy and/or therapies with biological agents. Azathioprine (AZA), 6-mercaptopurine (6-MP), methotrexate. and anti-TNF (infliximab, adalimumab) are reference drugs for IBD forms unresponsive to conventional t...

Background and study aims: Colon capsules display images from the moment they are ingested, making the study of other extracolonic areas possible. The aim of this study was to analyze the significance of these extracolonic findings. Patients and methods: In this single-center, prospective study, 165 patients underwent colon capsule endoscopy (CCE) between September 2009 and October 2012 to rule...

Abstract Aim To compare the proportions of malignancy between two modelled cohorts referred and investigated by our colorectal 2 WW referrals pathway. Methods Two were analysed from prospectively maintained 2WW database August 2018 to July 2019. One cohort (group A) included patients without anemia, rectal mass or overt bleeding. The other B) rest referrals. Data collected in each group total n...