REFERENCES 1. McKenna RW, Kyle RA, Kuehl WM, Grogan TM, Harris NL, Coupland RW. Plasma cell neoplasms. In: Swerdlow SH, Campo E, Harris NL, et al, eds. WHO Classification of tumours of haematopoietic and lymphoid tissues. 4th ed. Lyon, France: IARC, 2008:200-13. 2. De Schrijver I, Smeets P. Thyroid enlargement due to extramedullary plasmacytoma. JBR-BTR 2004;87:73-5. 3. Meccawy AA. Plasmacytoma...

B-Lymphoblastic Leukemia (B-ALL) is the second most common acute leukemia in adults. Its clinical manifestations include leukocytosis or leukopenia, anemia, and thrombocytopenia with an overall poor prognosis elderly patients. If relapse occurs, it commonly involves bone marrow but can also involve Extramedullary (EM) sites such as brain, testis, liver, spleen lymph nodes. Isolated extramedulla...

BACKGROUND Extramedullary disease is an uncommon manifestation in multiple myeloma and can either accompany newly diagnosed disease or develop with disease progression or relapse. We evaluated the impact of this disease feature on patients' outcome in the context of novel agents. DESIGN AND METHODS We analyzed clinical and biological features of extramedullary disease in 936 patients with mul...

INTRODUCTION  The extramedullary plasmocytoma is one of the localized forms of malignancy of the plasma cells, which has multiple myeloma main diagnosis. Its main site to the head and neck, but with a rare presentation in the larynx. OBJECTIVE  To describe a case of extramedullary plasmocytoma of the larynx, with literature review. CASE REPORT  Patient female, 49, referring to intermittent ...

Extramedullary relapse of acute lymphoblastic leukemia (ALL) is rare and has been primarily reported in pediatric patients or hematopoietic stem cell transplant recipients. We report a case of a 62-year-old woman who presented with relapsed ALL involving her kidneys, pancreas, and bone marrow 2 years after completing chemotherapy with a standard ALL protocol. Unfortunately, her extramedullary d...

Objective: To observe the therapeutic effect of microsurgery through hemilaminectomy approach on extramedullary spinal tumor. Methods: Hemilaminectomy was performed on 45 patients with extramedullary spinal tumor. Of the 45 patients, 35 had intradural extramedullary spinal tumors and 10 dumbbell-shaped spinal tumors. Spinal schwannoma occurred in 36 patients and spinal meningioma in 9 patients....

Primary extramedullary plasmacytoma is an indolent neoplasm that infrequently converts to multiple myeloma. Since cytogenetic data on extramedullary plasmacytoma are lacking, we studied 38 cases of this type of neoplasm by fluorescence in situ hybridization. Fourteen cases (37%) contained IGH breaks, including six with a t(4;14) translocation. No translocations t(11;14), t(14;16), t(8;14), nor ...

Extramedullary plasmacytomas and/or endobronchial plasmacytomas are rare conditions. We present this case due to its rarity. The patient who was diagnosed with extramedullary plasmacytoma of the right vocal cord ten years ago and nasopharynx two years ago was referred to our unit with hemoptysis. A suspicious lesion was detected in the right intermediate bronchus in the thoracic computed tomogr...