Effects of four organic solvents--methanol, trifluoroethanol, dimethylsulfoxide, and dimethylformamide (DMF)--on the ferritin-binding activity of three monoclonal mouse antibodies of IgG2a and IgG1 subclasses were studied. The ferritin-binding constants of monoclonal antibodies G10 and F11 (the IgG2a subclass) were increased 2-6-fold after incubation with DMF and removal of the organic solvent ...

A pure bacterial strain capable of aerobic biodegradation of fluorobenzene (FB) as the sole carbon and energy source was isolated by selective enrichment from sediments collected from a polluted site. 16S rRNA and fatty acid analyses support that strain F11 belongs to a novel genus within the alpha-2 subgroup of the Proteobacteria, possibly within a new clade related to the order Rhizobiales. I...

La floculation des asphaltnes est dŽcrite comme une transition thermodynamique conduisant ˆ la formation d'une nouvelle phase liquide riche en asphaltnes : le dŽp™t asphaltŽnique. Le modle thermodynamique choisi est l'Žquation d'Žtat de PengRobinson associŽe aux rgles de mŽlange d'Abdoul et PŽneloux fondŽes sur les contributions de groupes. Le brut est reprŽsentŽ par 33 pseudo-constituants....

Factor XI (FXI) deficiency is a rare autosomal recessive coagulation disorder most commonly found in Ashkenazi and Iraqi Jews, but it is also found in other ethnic groups. It is a trauma or surgery-related bleeding disorder, but spontaneous bleeding is rarely seen. The clinical manifestation of bleeding in FXI deficiency cases is variable and seems to poorly correlate with plasma FXI levels. Th...

Gynura procumbens (Lour.) Merr. belongs to the Asteraceae Family. The plant is a well-known traditional herb in South East Asia and it is widely used to treat inflammation, kidney discomfort, high cholesterol level, diabetic, cancer and high blood pressure. Our earlier study showed the presence of valuable plant defense proteins, such as peroxidase, thaumatin-like proteins and miraculin in the ...

Constitutional deficiency in factor XI (FXI) is a rare bleeding disorder in the general population, with the exception of Ashkenazi Jews. During the last decade, the detection of FXI-deficient patients has shifted from clinical screening identifying mostly severe bleeders to biological screening combining findings of prolonged activated partial thromboplastin time and FXI coagulation activity (...

Abstract Background Cilnidipine, a calcium channel blocker, is the first-line drug for hypertension and belongs to Biopharmaceutics Classification System II. To mitigate its extensive first-pass metabolism improve patient compliance, present study was performed develop characterize solid dispersion-based orodispersible tablets. Results The phase solubility with polyvinyl pyrrolidone 15% has sho...

Whereas the degradation of monoand dichlorinated anilines has been studied, very little is known about fluorinated anilines. Therefore, the objective of this study was to investigate, under aerobic conditions, the degradation of 2-, 3and 4-fluoroaniline by a previously isolated pure bacterium, designated as strain F11. This microorganism, identified as Labrys portucalensis, was isolated from a ...