نتایج جستجو برای: fabp5

تعداد نتایج: 302  

Journal: :Journal of lipid research 2006
Menno Hoekstra Miranda Stitzinger Eva J A van Wanrooij Ingrid N Michon J Kar Kruijt J Kamphorst M Van Eck E Vreugdenhil Theo J C Van Berkel Johan Kuiper

Liver parenchymal cells play a dominant role in hepatic metabolism and thereby total body cholesterol homeostasis. To gain insight into the specific pathways and genes involved in the response of liver parenchymal cells to increased dietary lipid levels under atherogenic conditions, changes in parenchymal cell gene expression upon feeding a Western-type diet for 0, 2, 4, and 6 weeks were determ...

Journal: :Frontiers in Pharmacology 2023

Breast cancer is the most prevalent malignancy among women. Doxorubicin (Dox) resistance was one of major obstacles to improving clinical outcome breast patients. The purpose this study investigate relationship between FABP signaling pathway and Dox in cancer. property MCF-7/ADR cells evaluated employing CCK-8, Western blot (WB), confocal microscopy techniques. glycolipid metabolic properties M...

Journal: :American Journal of Physiology-Lung Cellular and Molecular Physiology 2013

2013
Mas Rizky A. A. Syamsunarno Tatsuya Iso Hirofumi Hanaoka Aiko Yamaguchi Masaru Obokata Norimichi Koitabashi Kosaku Goto Takako Hishiki Yoshiko Nagahata Hiroki Matsui Motoaki Sano Masaki Kobayashi Osamu Kikuchi Tsutomu Sasaki Kazuhisa Maeda Masami Murakami Tadahiro Kitamura Makoto Suematsu YoshitoTsushima Keigo Endo Gökhan S. Hotamisligil Masahiko Kurabayashi

During prolonged fasting, fatty acid (FA) released from adipose tissue is a major energy source for peripheral tissues, including the heart, skeletal muscle and liver. We recently showed that FA binding protein 4 (FABP4) and FABP5, which are abundantly expressed in adipocytes and macrophages, are prominently expressed in capillary endothelial cells in the heart and skeletal muscle. In addition,...

Journal: :Cellular signalling 2011
Michael G Borland Combiz Khozoie Prajakta P Albrecht Bokai Zhu Christina Lee Tejas S Lahoti Frank J Gonzalez Jeffrey M Peters

Peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) function and receptor cross-talk with other nuclear receptors, including PPARγ and retinoic acid receptors (RARs), was examined using stable human HaCaT keratinocyte cell lines over-expressing PPARβ/δ or PPARγ. Enhanced ligand-induced expression of two known PPAR target genes, adipocyte differentiation-related protein (ADRP) and angiopoie...

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