In this work we explore direct reconstruction algorithms for Computed Tomography, based on principles of Filtered Back-Projection (FBP). Special attention is given to the problem of image reconstruction in Region Of Interest (ROI) from truncated projections. In the proposed linear reconstruction scheme the ramp filter of FBP is replaced with a statistically trained spatially-variant 2-D convolu...

The reconstruction of dynamic PET data is usually performed using filtered backprojection algorithms (FBP). This method is fast, robust, linear and yields reliable quantitative results. However, the use of FBP for low count data, such as dynamic PET data, generally results in poor visual image quality, exhibiting high noise, disturbing streak artifacts and low contrast. These signal-to-noise ra...

BACKGROUND Iterative reconstruction can reduce image noise and thereby facilitate dose reduction. PURPOSE To evaluate qualitative and quantitative image quality for full dose and dose reduced head computed tomography (CT) protocols reconstructed using filtered back projection (FBP) and adaptive statistical iterative reconstruction (ASIR). MATERIAL AND METHODS Fourteen patients undergoing fo...

BACKGROUND Positron emission tomography (PET) studies using 15O-labeled CO2, O2, and CO have been used in humans to evaluate cerebral blood flow (CBF), the cerebral oxygen extraction fraction (OEF), and the cerebral metabolic rate of oxygen (CMRO2) and cerebral blood volume (CBV), respectively. In preclinical studies, however, PET studies using 15O-labeled gases are not widely performed because...

Digital Breast Tomosynthesis (DBT) is a technology that creates three dimensional (3D) images of breast tissue. Tomosynthesis mammography detects lesions that are not detectable with other imaging systems. If image reconstruction time is in the order of seconds, we can use Tomosynthesis systems to perform Tomosynthesis-guided Interventional procedures. This research has been designed to study u...

A mathematical framework for quantitative SPECT (single photon emission computed tomography) reconstruction of the heart is presented. An efficient simultaneous compensation approach to the reconstruction task is described. The implementation of the approach on a digital computer is delineated. The approach was validated by experimental data acquired from chest phantoms. The phantoms consisted ...

BACKGROUND Coronary computed tomography angiography (CCTA) requires high spatial and temporal resolution, increased low contrast resolution for the assessment of coronary artery stenosis, plaque detection, and/or non-coronary pathology. Therefore, new reconstruction algorithms, particularly iterative reconstruction (IR) techniques, have been developed in an attempt to improve image quality with...

OBJECTIVES To compare image quality on computed tomographic (CT) images acquired with filtered back-projection (FBP), adaptive statistical iterative reconstruction (ASIR) and model-based iterative reconstruction (MBIR) techniques in CT kidney/ureter/bladder (KUB) examination. METHODS Eighteen patients underwent standard protocol CT KUB at our institution. The same raw data were reconstructed ...

BACKGROUND & OBJECTIVES Preoperative localization of parathyroid lesions is essential for improving the results in patients with primary hyperparathyroidism. The purpose of this study was to evaluate retrospectively the value of technetium-99m (Tc-99m) methoxyisobutylisonitrile (MIBI) single photon emission computed tomography (SPECT) and to compare the diagnostic accuracy of iterative reconstr...

X-ray inspection of Carbon Fiber Reinforced Polymer (CFRP) is time consuming. With classical reconstruction methods, many projections of the object from different orientations are required to obtain high quality reconstructions of the interior fiber composition. In this work, we propose to reconstruct the interior of the CFRP samples with a Neural Network Filtered Backprojection (NN-FBP) method...