This paper considers the economic lot and delivery scheduling problem in a two-echelon supply chains, where a single supplier produces multiple components on a flexible flow line (FFL) and delivers them directly to an assembly facility (AF). The objective is to determine a cyclic schedule that minimizes the sum of transportation, setup and inventory holding costs per unit time without shortage....

This final rule makes several changes affecting Medicare Part B payment. The changes include: implementation of resource-based malpractice insurance relative value units (RVUs); refinement of resource-based practice expense RVUs; payment for physician pathology and independent laboratory services; discontinuous anesthesia time; diagnostic tests; prostate screening; use of CPT modifier -25; qual...

molecular farming has been considered as a secure and economical approach for production of biopharmaceuticals. human tnf related apoptosis inducing ligand (trail) as a promising biopharmaceutical candidate has been produced in different expression hosts. however, little attention has been paid to molecular farming of the trail in spite of numerous advantages of plant expression systems. theref...

ooperative fabrication was a key factor in building the Near Earth Asteroid Rendezvous (NEAR) spacecraft within the cost and schedule constraints dictated by the NASA Discovery Program. Because many of the traditional barriers between the engineering and the fabrication teams were avoided on NEAR, APL reaped the benefits of cooperative planning, design for ease of fabrication and assembly, and ...