Flavonoids are polyphenolic compounds with potential antioxidant activity via multiple reduction capacities. Oxidation of cellular lipids has been implicated in many diseases. Consequently, this study has assessed the ability of several dietary flavonoid aglycones to suppress lipid peroxidation of hepatic microsomes derived from rats deficient in the major lipid soluble antioxidant, dα-tocopher...

1. The biliary and urinary excretion of (+)-[U-(14)C]catechin was studied in normal male rats after a single injection of the flavonoid. 2. In rats large amounts of radioactivity (33.6-44.3% of the dose in 24h) were excreted in the bile as two glucuronide conjugates [one of which was a (+)-catechin conjugate] and three other unconjugated metabolites. 3. Excretion of radioactivity in the urine w...

The present study determined the phenolic and flavonoid contents in Amomum chinense C. leaf extracts obtained using four extracting solvents(distilled water, 80% methanol, 80% ethanol and 80% acetone)with various extraction times (6h, 12h and 24h) at 37oC. All extraction conditions significantly (p <0.05) affected the phenolic contents and antioxidant activity of the leaf extracts. The optimal ...

Investigations have been made to develop an efficient protocol for identification and quantification of phenolic acids and flavonoids in hairy roots (HR) of Hypericum perforatum L. HR were induced from root segments of in vitro grown seedlings from H. perforatum, after co-cultivation with Agrobacterium rhizogenes A4. Transgenic status of HR was confirmed by PCR analysis using rolB specific prim...

BACKGROUND Acacia hydaspica belongs to family leguminosae possess antioxidant, anti-inflammatory and anticancer activities. During our search for antioxidant compounds from A. hydaspica, we carried out bioassay guided fractionation and obtained antioxidant compounds with free radical scavenging activity. MATERIALS AND METHODS The polyphenol compounds in the plant extract of A. hydaspica were ...

Desmodium adscendens plant is widely used as juice or tea in various parts of the world against a wide range of diseases. This study determines the quality and the quantity of polyphenols, flavonoids, anthocyanins, and tannins in D. adscendens leaves by UV-spectrophotometry and RP-HPLC methods. In addition, the antioxidant capacity of these phenolic compounds is evaluated by ABTS (2,2'-azino-bi...

pomegranate (punica granatum l.), lythraceae, is mainly grown in mediterranean region. it is one of the major cultivated productions of iran, which have been used in folk medicine for many centuries. it has been proved that pomegranate has a high antioxidant activity and is effective in the prevention of atherosclerosis. this study compares the antioxidant activity, total phenolic and flavonoid...

Eight Salvia L. species including S. spinosa L., S. reuterana Boiss., S. macrosiphon Boiss., S. syriaca L., S. nemorosa L., S. virgata Jacq., S. sharifii Rech. f. & Esfand. and S. mirzayanii Rech. f. & Esfand. were studied for flavonoid compounds. These constituents were analyzed using two-dimensional maps on silica gel 60F thin layer chromatography. The flavonoid compounds of each species were...

The facilitative glucose transporter, GLUT4, mediates insulin-stimulated glucose uptake in adipocytes and muscles, and the participation of GLUT4 in the pathogenesis of various clinical conditions associated with obesity, visceral fat accumulation and insulin resistance has been proposed. Glucose uptake by some members of the GLUT family, mainly GLUT1, is inhibited by flavonoids, the natural po...

The presence of the procyanidins epicatechin-( 4j3-8)-catechin. epicatechin..{ 4j3-6)-catechin. catechin( 4a-8)-catechin. epicatechin-( 4j3-8 >-epicatechin-( 4j3-8)-epicatechin-{ 4138)-catechin. and epicatechin-(4j3-8)-epicatechin-(4j3-6)catechin in tile phloem of PillU.f raeda demonstrated heterogeneity in the location of the interftavanoid bonds in oligomeric pro...