the main objective of the present study was to formulate gastroretentive effervescent sustained release drug delivery systems of risperidone floating tablets with the help of methocel® k15, ethocel® standard 7fp premium, eudragit ® rs100 sustained release polymers to improve its safety profile, bioavailability and patient compliance. risperidone floating tablets were formulated by wet granulati...

The way humans establish communication depends on the generation and conveyance of meaning. Linguistically, meaning in information is dependent on the meaning that is ascribed to signifiers in the context of the communication. These signifiers can include items such as words, phrases, signs, and symbols. Conveyance of meaning may, however, imprecise and prone to error. The meaning of informatio...

the islamic fundamentalism which turned into a major social course in many arab countries in 1980s, has inspired a wide spectrum of theoretical analyses. in this article we have attempted to evaluate this course by the method of discoursive analyse. despite many dissimilarities that differentiate islamic fundamentalism from other political , and even religious reformist, movements regarding met...

An oral sustained-release floating tablet formulation of metformin HCl was designed and developed. Effervescence and swelling properties were attributed on the developed tablets by sodium bicarbonate and HPMC-PEO polymer combination, respectively. Tablet composition was optimized by response surface methodology (RSM). Seventeen (17) trial formulations were analyzed according to Box-Behnken desi...

for prolonging the time that drug remains in stomach, new methods used as floating drug delivery systems, that available in various forms such as floating tablets. these systems enhance drug absorption and decrease plasma concentration fluctuations. iron deficiency and its inadequate absorption in diet are of community health problems. for prolonging the time that drug remains in stomach, new m...

This research aims to identify the representation of fantasy comedy and explain sign system represent that is found in Turning Red movie posters. was descriptive qualitative because result discussed descriptively. The data this signifier signifier, verbal signs represented by text which consists words, phrases, clauses, sentences on posters, non-verbal picture. Then, color meaning From research...

the purpose of this study is to examine the meaning transformation of despotism signifier from safavid era to the rising of iranian despotism discourse in qajar era. the method is archaeology and the study is focused on the relations of the meaning transformation with discourse practices. pre-modern texts were investigated for the significance of despotism. the results suggested that these sign...