We report the synthesis and photophysical properties of three biperylene-based dendrimers, which show red fluorescence in water. A fluorescence microscopy study demonstrated uptake of biperylene-based dendrimers in living cells. Our results indicate that these biperylene-based dendrimers are promising candidates in fluorescence imaging applications with the potential as therapeutic carriers.

Fluorescence microscopy is one of the most used imaging modalities in molecular biology and living specimens. To increase image contrast spatial resolution, different type fluorescence has been developed. This review introduces three main types microscopy: wild-field microscopy, confocal total internal reflection microscopy. The basic principles are similar but with modifications, which also in...