نتایج جستجو برای: fmod

تعداد نتایج: 119  

Journal: :Investigative ophthalmology & visual science 2011
Shea Ping Yip Kim Hung Leung Po Wah Ng Wai Yan Fung Pak Chung Sham Maurice K H Yap

PURPOSE. To investigate the relationship between high myopia and single nucleotide polymorphisms (SNPs) in six proteoglycan genes: aggrecan (ACAN), fibromodulin (FMOD), decorin (DCN), lumican (LUM), keratocan (KERA), and epiphycan (EPYC). These genes were selected for study because they are involved in induced myopia in animals and/or are within the human MYP3 locus identified by linkage analys...

2016
Qingying Meng Zhe Ying Emily Noble Yuqi Zhao Rahul Agrawal Andrew Mikhail Yumei Zhuang Ethika Tyagi Qing Zhang Jae-Hyung Lee Marco Morselli Luz Orozco Weilong Guo Tina M. Kilts Jun Zhu Bin Zhang Matteo Pellegrini Xinshu Xiao Marian F. Young Fernando Gomez-Pinilla Xia Yang

Nutrition plays a significant role in the increasing prevalence of metabolic and brain disorders. Here we employ systems nutrigenomics to scrutinize the genomic bases of nutrient-host interaction underlying disease predisposition or therapeutic potential. We conducted transcriptome and epigenome sequencing of hypothalamus (metabolic control) and hippocampus (cognitive processing) from a rodent ...

2016

Cognitive impairment in mild degree have reported in most of the patients with FM [1,2]. And also; patients with FM have reported that they were unable to perform demanding cognitive tasks at their previous level [2]. Especially patients with jobs that have high cognitive/technical demands are likely to perceive their performance in the workplace to be seriously compromised. In addition many of...

Journal: :Neuroscience 2010
G Rance L A Corben E Du Bourg A King M B Delatycki

Friedreich ataxia (FRDA) is a neurodegenerative disease affecting motor and sensory systems. This study aimed to investigate the presence and perceptual consequences of auditory neuropathy (AN) in affected individuals and examine the use of personal-FM systems to ameliorate the resulting communication difficulties. Ten individuals with FRDA underwent a battery of auditory function tests and the...

1997
Torsten Dau

In this thesis a new modeling approach is developed which is able to predict human performance in a variety of experimental conditions related to modulation detection and modulation masking. Envelope uctuations are analyzed with a modulation lterbank. The parameters of the lterbank were adjusted to allow the model to account for modulation detection and modulation masking data with narrowband c...

2004
Montri Maleewong Roger Grimshaw Jack Asavanant

We consider steady free surface two-dimensional flow due to a localized applied pressure distribution under the effects of both gravity and surface tension in water of a constant depth, and in the presence of a uniform stream. The fluid is assumed to be inviscid and incompressible, and the flow is irrotational. The behaviour of the forced nonlinear waves is characterized by three parameters: th...

Journal: :Annals of human biology 2013
V P Wickramasinghe C Arambepola D M P S Bandara M Abeysekera S Kuruppu P Dilshan B S Dissanayake

BACKGROUND Excess body fat leads to obesity-related morbidity and population/ethnicity-specific cut-off values of anthropometric measures are useful for better diagnosis. This study assesses the suitability of newly-developed Sri Lankan anthropometric cut-off values in the diagnosis of obesity in Sri Lankan children. METHODS A cross-sectional study was conducted at University of Colombo, Sri ...

2016
Tomohiro Kayama Masaki Mori Yoshiaki Ito Takahide Matsushima Ryo Nakamichi Hidetsugu Suzuki Shizuko Ichinose Mitsuru Saito Keishi Marumo Hiroshi Asahara

Mechanoforces experienced by an organ are translated into biological information for cellular sensing and response. In mammals, the tendon connective tissue experiences and resists physical forces, with tendon-specific mesenchymal cells called tenocytes orchestrating extracellular matrix (ECM) turnover. We show that Mohawk (Mkx), a tendon-specific transcription factor, is essential in mechanore...

Journal: :The Journal of Cell Biology 2000
Yoichi Ezura Shukti Chakravarti Åke Oldberg Inna Chervoneva David E. Birk

Collagen fibrillogenesis is finely regulated during development of tissue-specific extracellular matrices. The role(s) of a leucine-rich repeat protein subfamily in the regulation of fibrillogenesis during tendon development were defined. Lumican-, fibromodulin-, and double-deficient mice demonstrated disruptions in fibrillogenesis. With development, the amount of lumican decreases to barely de...

2005
A. Iulian Apostoaei

A model describing transport of I in the environment was developed by SENES Oak Ridge, Inc., for assessment of radiation doses and excess lifetime risk from I atmospheric releases from Oak Ridge Reservation in Oak Ridge, Tennessee, and from Idaho National Engineering and Environmental Laboratory in southeast Idaho. This paper describes the results of an exercise designed to test the reliability...

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