One of the most demanding areas for performance data and information in the public sector is city administrations. This paper presents how the model of a computerized PM system works through examples of its implementation in a city administration, following the steps of PDCA Cycle, complemented by the following concepts: Balanced Scorecard; Performance Measurement System Report of the Foundatio...

Corrosion protection and surface properties of Magnesium (Mg) containing 51 ppm Fe (HP-Mg) 341 (CP-Mg) were assessed by EIS, AFM/SKPFM, photoluminescence spectroscopy in NaCl solutions with/without fumarate (Fum), 2,5-pyridinedicarboxylate (PDCA) salicylate (Sal) carboxylates. The PDCA was effective corrosion inhibition HP-Mg CP-Mg, while the Sal efficient CP-Mg only. Volta potential (VPD) chan...

Vibrio cholerae is a Gram-negative pathogen which causes acute diarrhoeal disease, cholera by the expression of virulence genes through quorum sensing (QS) mechanism. The QS circuit of V. cholerae is controlled by the global quorum regulator, LuxO, which at low cell density (LCD) state produces major virulence factors such as, toxin co-regulated pilus (TCP) and cholera toxin (CT) to mediate inf...

CD44 and prostate stem cell antigen (PSCA) have been investigated as two biomarkers for various cancers. However, either CD44 or PSCA expression alone has limited clinical value. In the present study, the expression of CD44 and PSCA in human pancreatic ductal adenocarcinoma (PDAC) and their values in prognosis were investigated by immunohistochemistry (IHC) and Kaplan-Meier method. The results ...

Post-translational ribosomal protein hydroxylation is catalyzed by 2-oxoglutarate (2OG) and ferrous iron dependent oxygenases, and occurs in prokaryotes and eukaryotes. OGFOD1 catalyzes trans-3 prolyl hydroxylation at Pro62 of the small ribosomal subunit protein uS12 (RPS23) and is conserved from yeasts to humans. We describe crystal structures of the human uS12 prolyl 3-hydroxylase (OGFOD1) an...

Viral dsRNA can be found at the site of inflammation in RA patients, and intra-articular injection of dsRNA induces arthritis by activating type I IFN signaling in mice. Further, DCs, a major source of IFN-α, can be found in the synovium of RA patients. We therefore determined the occurrence of DCs in dsRNA-induced arthritis and their ability to induce arthritis. Here, we show, by immunohistoch...