BACKGROUND No data regarding metformin effects on follicular fluid anti-Müllerian hormone (AMH) levels were to date available in literature. The aim of the present study was to evaluate in patients with polycystic ovary syndrome (PCOS) whether metformin administration affects serum and follicular AMH levels, and whether this is related to ovarian response to the treatment. METHODS Twenty youn...

introduction: the contraception has been practiced for over 4000 years and the prevalence of contraceptive use has increased worldwide.the existing methods of contraception are not perfect and their acceptability is limited by side effects and inconvenience.thus there is a real need for new methods of contraception to be developed. the effects of the follicular fluid on the pregnancy rate has b...

The one-humped camel (Camelus dromedarius) is a seasonal breeder with a relatively short breeding period, when increased ovarian activity is exhibited (Shalash, 1965,1980; Nawito, Shalash, Hoppe ¿St Rakha, 1967 ; Novoa, 1970). In Israel, the normal breeding season occurs from December to early April. Female camels come into heat during this period and exhibit mainly follicular activity; there i...

OBJECTIVE A small amount of LH is necessary for 17beta-estradiol production in the ovarian follicle. Human menopausal gonadotropin (hMG) contains equal amounts of FSH and LH activity, whereas recombinant FSH is a gonadotropin preparation without LH. The aim of the present randomized study was to investigate whether ovarian stimulation treatment with recombinant FSH or hMG resulted in different ...

BACKGROUND This study aimed to determine amino acid (AA), ammonia and urea concentrations in human ovarian follicular fluid and to compare these concentrations with those in the circulation. METHODS Samples of pre-ovulatory follicular fluid and peripheral venous blood were obtained from 14 IVF patients. High-performance liquid chromatography (HPLC) measurements of 25 AAs were the main outcome...

While the hypothalamic-pituitary-gonadal axis is crucial for the function of the gonads, non-endocrine regulatory influences are exerted by other factors within the gonads. Among these factors are neurotransmitters, such as catecholamines. Several types of receptors for catecholamines exist in the gonads on vascular or endocrine cells. Their activation can alter blood flow, steroidogenesis and ...

The aim of this work was to study the antioxidant enzymatic defences in human follicular fluid and investigate their possible changes during reproductive ageing. To this end, we tested the specific activities and protein expression of enzymes involved in reactive oxygen species (ROS) scavenging and in detoxification of ROS byproducts in follicular fluid from young (range 27-32 years, n = 12) an...

Potential antimicrobial activity of follicular fluid and its selectivity remains open questions in field of human and animal reproduction. In our work we examine antimicrobial activity of porcine follicular fluid on coliform bacteria, as Gram-negative, and B. cereus, as Gram-positive, by incubation of different dilatations of bacteria with follicular fluid in cultivation medium and microbiologi...

Our previous study reported microorganisms in human follicular fluid. The objective of this study was to test human follicular fluid for the presence of microorganisms and to correlate these findings with the in vitro fertilization (IVF) outcomes. In this study, 263 paired follicular fluids and vaginal swabs were collected from women undergoing IVF cycles, with various causes for infertility, a...