In the literature there is no clear evidence of a relationship between thyropathies and fragility fractures. The aim of our study is to define the prevalence of thyroid disease in a study sample made up of subjects with fragility fractures and from the same geographical area. We retrospectively studied the "hospital discharge records" (HDR) in the Apulian Database for the period 2008-2013 in or...

The main results are 1) definition of fragility, antifragility and model error (and biases) from missed nonlinearities and 2) detection of these using a single “fast-and-frugal”, model-free, probability free heuristic. We provide an expression of fragility and antifragility as negative or positive sensitivity to convexity effects, i.e., dispersion and volatility (a variant of negative or positi...

We introduce a general framework for models of cascade and contagion processes on networks, to identify their commonalities and di erences. In particular, models of social and nancial cascades, as well as the ber bundle model, the voter model, and models of epidemic spreading are recovered as special cases. To unify their description, we de ne the net fragility of a node, which is the di erence...

This paper presents the formulation of a time-dependent seismic fragility format for bridges, as well as new insights into the potential effects of aging and deterioration on seismic vulnerability traditionally neglected in fragility modeling, including joint impacts of multiple component deterioration not investigated to date. The study evaluates the impact of lifetime exposure to chlorides fr...

This paper presents a statistical analysis of structural fragility curves. Both empirical and analytical fragility curves are considered. The empirical fragility curves are developed utilizing bridge damage data obtained from the 1995 Hyogo-ken Nanbu (Kobe) earthquake. The analytical fragility curves are constructed on the basis of the nonlinear dynamic analysis. Two-parameter lognormal distrib...

Bridges are essential lifelines for transportation networks during and after an earthquake event, providing routes for emergency response and evacuations. For this reason, bridge fragility modeling has been a major focus in earthquake research, as fragility analysis aids in the post-event determination of possible damage of bridges as well as in pre-event mitigation planning. While fragility an...

The aim of this study was to assess the usefulness of the inbred rat model for studies of genetic influences on skeletal fragility. We characterized bone mass, geometry, and skeletal biomechanics in 11 inbred strains of rats. This study showed that considerable variation exists in bone structure, areal bone mineral density (aBMD), and fragility phenotypes among inbred strains of rats. Interesti...

We examine the sensitivity and surface bias of convolved DGLV radiative and elastic loss in a realistic geometry including Bjorken expansion. We find that this more faithful treatment of the medium density is not a priori reproducible via fixed length approximations, and neither the fragility nor the surface emission of BDMPS-based models is seen.

to fracture. However, bones fracture for different reasons, so there are several different biomechanical definitions of bone fragility. One function of bones is to carry loads. Fractures occur when loads exceed the bone strength, so weakened bones should be considered fragile. For example osteoporotic vertebral bodies might fracture during normal daily activities like opening a window or rising...

REINHOLD, B.M., M.R.C.P., D.C.H. AND 1)AvID YI-YUNG HSIA, M.D. I ORDER to obtains a better ttnderstanding of tise factors causitsg destruction of human erythrocytes its vivo, a number of methods have beets devised to test their susceptil)ihty to destructions by various forces applied in vitro. By manipulation of temperature, pH, osmotic equilih)rium and by the addition of hemolysitis, ithas bee...