Aim was to determine if a serum levels of free testosterone and selected eight hormones are in correlation with potency and libido problems in aging male. Male population older then 45 years of two Slavonian villages was called for voluntary examination. Every patient filled a questionnaire concerning medical history, operations and potency and libido problems. Based on answers we formed six gr...

OBJECTIVE A potential risk of testosterone replacement therapy is an increase in the incidence of prostate cancer, but it is unclear whether higher levels of serum testosterone are associated with a higher risk of prostate cancer. We prospectively evaluated serum androgen concentrations and prostate cancer risk. METHOD Included were 794 members of the Baltimore Longitudinal Study of Aging. We...

Background: Women suffer more often from depression than men. Social research suggests that high androgen levels cause aggressive behavior in men and women, and consequently cause depression. The purpose of this study was to determine serum levels of androgens, especially testosterone, in patients with depression. Material and methods: In this case-controlled study, we measured serum testoste...

Testosterone deficiency is a common and often unrecognized disorder impacting the lives of many men. Symptoms related to low testosterone are relatively non-specific and clinicians must therefore ensure that a patients' symptomatology is supported by a biochemical profile suggestive of testosterone deficiency. There are many options available to determine a patient's testosterone level and labo...

CONTEXT Lower circulating testosterone concentrations are associated with metabolic syndrome, type 2 diabetes, carotid intima-media thickness, and aortic and lower limb arterial disease in men. However, it is unclear whether lower testosterone levels predict major cardiovascular events. OBJECTIVE We examined whether lower serum testosterone was an independently significant risk factor for sym...

INTRODUCTION Combined hormonal contraceptives (CHCs) use is becoming an increasingly recognized causes of vestibulodynia. AIM This study aims to describe pre- and posttreatment vestibular pain, sex hormone binding globulin (SHBG), and calculated free testosterone levels in women undergoing treatment for vestibulodynia. METHODS This was a chart review of 50 premenopausal women who presented ...

A method for rapidly determining bound and free testosterone in human plasma is evaluated and described, in which dextran-coated charcoal is used to separate bound and free testosterone. Intra- and inter-assay CV's were 1.9 and 3.8%, respectively. At least 50% of the "bound" testosterone was associated with species that behaved like sex steroid hormone-binding globulin on Sephadex G-25 chromato...

OBJECTIVE Previous reports of an association between low testosterone levels and diabetes risk were often confounded by covariation of sex hormone-binding globulin (SHBG) and testosterone measurements. Measurements of bioavailable and free testosterone, more reliable indexes of biologically active testosterone, were examined for their associations with markers of insulin resistance and body fat...

objectives: this study was conducted in order to analyse the effect of flat pyramid loading pattern (fplp) weight training on salivary steroids levels in strength training athletes. methods: eleven elite male weightlifters trained six days per week for one month. five millilitres of unstipulated whole saliva was obtained pre- and five minutes post-exercise at days first, 15th, and 30th. results...

CONTEXT The prevalence of frailty increases, whereas testosterone decreases, as men age. Low testosterone may be a risk factor for development of this syndrome. OBJECTIVE Our objective was to determine whether testosterone levels are associated with frailty. DESIGN We conducted a prospective cohort study. SETTING AND PARTICIPANTS Between 2001 and 2004, frailty was assessed in 3616 communi...