BACKGROUND Improved adherence to inhaled corticosteroids (ICS) is recognized as an important factor in reduced morbidity, mortality and consumption of health care resources. The present study was designed to replicate previous reports of patient adherence with fluticasone/salmeterol in a single inhaler (FSC), fluticasone and salmeterol in separate inhalers (FP+SAL), fluticasone and montelukast ...

Rat liver secretory component is synthesized as an integral membrane protein (mSC) and cleaved to an 80-kD soluble form (fSC) sometime during transcellular transport from the sinusoidal to the bile canalicular plasma membrane domain of hepatocytes. We have used 24-h monolayer cultures of rat hepatocytes to characterize the conversion of mSC to fSC. Cleavage of mSC in cultured hepatocytes is inh...

High concentration of volatile nanoparticles (NPs) formed in vehicular exhaust may lead to adverse health effects, and a clear understanding of the nucleation mechanisms of these particles remains to be achieved. We investigate the role of H2SO4–H2O binary homogeneous nucleation (BHN) in the formation of NPs in the diluting vehicular exhaust, using a recently developed kinetic H2SO4–H2O BHN mod...

Moderate-resolution imaging spectroradiometer (MODIS) snow-cover products have relatively low accuracy over the Tibetan Plateau because of its complex terrain and shallow, fragmented snow cover. In this study, fractional snow-cover (FSC) mapping algorithms were developed using a linear regression model (LR), a linear spectral mixture analysis model (LSMA) and a back-propagation artificial neura...

BACKGROUND Inhaled corticosteroid/long-acting β2-agonist combinations (ICS/LABA) have emerged as first line therapies for chronic obstructive pulmonary disease (COPD) patients with exacerbation history. No randomized clinical trial has compared exacerbation rates among COPD patients receiving budesonide/formoterol combination (BFC) and fluticasone/salmeterol combination (FSC) to date, and only ...

Zirconium-89 is an emerging radionuclide for positron emission tomography (PET) especially for biomolecules with slow pharmacokinetics as due to its longer half-life, in comparison to fluorine-18 and gallium-68, imaging at late time points is feasible. Desferrioxamine B (DFO), a linear bifunctional chelator (BFC) is mostly used for this radionuclide so far but shows limitations regarding stabil...

Diffusion coefficients (D) of hydrogen in fused silica capillaries (FSC) were determined between 296 and 523 K by Raman spectroscopy using CO2 as an internal standard. FSC capsules (3.25 10 4 m OD, 9.9 10 5 m ID, and 0.01 m long) containing CO2 and H2 were prepared and the initial relative concentrations of hydrogen in these capsules were derived from the Raman peak-height ratios between H2 (ne...

background: β-thalassemia is a common autosomal recessive disorder resulting from over 200 different mutations of beta glo­bin genes. the aim of the present study was to identify the distribution and frequency of the most com­mon β-thalassemia mu­tations among the population of isfahan province in central iran. methods: the data presented here were derived from a total of 114 β-thalassemia chro...

OBJECTIVE To report our experience with 200 cases of basal cell carcinoma (BCC) in 192 patients treated with an enhanced frozen-section control (FSC) technique using stereoscopic microdissection of surgical margins. METHODS Retrospective series of 192 patients with 200 lesions diagnosed as BCC of the periocular region. All were excised en bloc with 1-mm margins beyond the clinically apparent ...

This paper investigates the internal structure of finite small clauses (FSC). I will propose that a FSC is base-generated at Spec-CP and a null operator is involved to check the formal features of the embedded T and turn a sentence into a predicate.