Diagnosis of pigmented lesions of the mouth and oral mucosal tissues is challenging. Even though epidemiology may be of some help in orientating the clinician and even though some lesions can be diagnosed on clinical grounds alone, the definitive diagnosis requires histopathological examination. We report a case of pigmented fungiform papillae on the tongue secondary to iron deficiency anaemia....

Subjects were asked to assess the bitterness of one 6-n-propyl-2-thiouracil (PROP) and two quinine HCl (QHCl) concentrations presented via filter papers of varying sizes. The number of taste papillae stimulated by these filter papers was counted in each individual. Whole mouth sensitivity to PROP was determined in a separate session. In support of other demonstrations of spatial summation, thes...

Although taste buds are trophically dependent on their innervation, cross-reinnervation experiments have shown that their gustatory sensitivities are determined by the local epithelium. Both the gustatory G-protein, alpha-gustducin, and the cell-surface carbohydrate, the A blood group antigen, are expressed by significantly fewer fungiform than vallate taste cells in the rat. In these experimen...

BACKGROUND Pain and sensory changes due to lingual nerve injury are one of the most common alterations that follow surgical removal of third molar. They are usually transient but other less common complications, such as the atrophy of fungiform papillae, have an uncertain prognosis. CASE DESCRIPTION We report a case of a 34-year-old woman who presented a unilateral lingual atrophy of fungifor...

The localization of Mg++ activated adenosine triphosphatase (ATPase) activity in rat fungiform taste buds was demonstrated by electron microscopic histochemistry. Reaction product was found on the cell membrane of the taste cells, but not within their cytoplasm. Especially strong reaction occurred in the taste pore. Besides, enzymes were observed in axon-Schwann cell and axon-type I cell inters...

BACKGROUND There are five common, independent measures used to characterize taste function in humans: detection and recognition thresholds (DT and RT), suprathreshold intensity ratings of prototypical tastants, propylthiouracil (PROP) bitterness intensity, and fungiform papillae (FP) number. METHODS We employed all five methods to assess taste function of 65 women (21.5 ± 4 years, BMI 22.3 ± ...

After the complete removal of submandibular gland surgically, morphological alterations, and the effects of EGF given orally on these alterations were investigated. In the study, 30 adult female SpraqueDawley rats were used, which were divided equally into three groups: Control group; sialoadenectomy group ; sialoadenectomy + epidermal growth factor group . Following a three week period of reco...