Wnts are secreted proteins that are essential for a wide array of developmental and physiological processes. They signal across the plasma membrane by interacting with serpentine receptors of the Frizzled (Fz) family and members of the low-density-lipoprotein-related protein (LRP) family. Activation of Fz-LRP promotes the stability and nuclear localization of beta-catenin by compromising the ab...

Enzymatic disproportionation of cyclohex-2-enone was screened using Agilent J&W GC columns. Published by Elsevier B. V. Essential oils of six Juniperus taxa indigenous in Greece Parasitology Research, 110, 1829-1839 (2012) Tags F. Vourlioti-Arapi et al. HP-5ms, 7890A GC, 5957C MSD, clinical research, disease research Abstract Juniper essential oils were analyzed on an Agilent J&W HP-5ms column ...

Drosophila Wingless (Wg) is a secreted signaling protein of the Wnt family. Mutations in the wg gene disrupt the patterning of embryonic segments and their adult derivatives. Wg protein has been shown in cell culture to functionally interact with DFz2, a receptor that is structurally related to the tissue polarity protein Frizzled (Fz). However, it has not been determined if DFz2 functions in t...

Two studies examined EEG co-activation (coherence) between the verbal-analytical (T3) and motor planning (Fz) regions during a golf putting task. In Study 1, participants with a strong propensity to consciously monitor and control their movements, determined psychometrically by high scores on a movement specific Reinvestment Scale, displayed more alpha2 T3-Fz co-activation than participants wit...

In this study, the effects of Yb: YAG laser welding parameters on microstructure and mechanical properties AA6061-T4 joints were analysed. Samples without any defects such as porosity, melt pool collapse, hot cracking produced with different parameters. Energetic processing had a significant influence fusion zone (FZ) heat-affected (HAZ) dimensions, in addition to local global properties. The w...

Frizzled (Fz) signaling regulates cell polarity in both vertebrates and invertebrates. In Drosophila, Fz orients the asymmetric division of the sensory organ precursor cell (pI) along the antero-posterior axis of the notum. Planar polarization involves a remodeling of the apical-basal polarity of the pI cell. The Discs-large (Dlg) and Partner of Inscuteable (Pins) proteins accumulate at the ant...

Cells in a variety of developmental contexts sense extracellular cues that are given locally on their surfaces, and subsequently amplify the initial signal to achieve cell polarization. Drosophila wing cells acquire planar polarity along the proximal-distal (P-D) axis, in which the amplification of the presumptive cue involves assembly of a multiprotein complex that spans distal and proximal bo...

UNLABELLED We present a comparative study of thermal donor (TD) center formation mechanisms as a result of carbon ion implantation into float zone (FZ-Si) and Czochralski (Cz-Si) silicon crystals. The kinetics of the TD center formation and transformation of their structure during annealing have been investigated. Also, the TD center formation takes place after additional oxygen implantation in...

Molecules labeled in green and blue play positive and negative roles in Wnt/β-catenin signaling, respectively. Molecules that are labeled in both colors have dual roles. (Top left) Wnt biogenesis. A lipid modification is added to Wnt ligands by Porc in the endoplasmic reticulum (ER). Wnt ligands are glycosylated in the ER and Golgi and require Wls (also known as Evi) to traffic through the Golg...

1 Department of Genetics and Microbiology, M. Curie-Sklodowska University, Akademicka 19, Lublin 20-033, Poland 2 Division of Structural Biochemistry, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Parkallee 4a/c, Borstel D-23845, Germany; E-Mails: [email protected] (K.A.D.); [email protected] (O.H.) 3 Division of Bioanalytical Chemistry, Research Center Borstel, Lei...