Allium vegetables (onions, leeks, chives) and in particular garlic have been claimed to have health-promoting potential. This study was conducted to get insight into the perspectives for monitoring the intake of garlic by a biomarker approach. Chemically, the biomarker results from exposure to gamma-glutamyl-S-allyl-l-cysteine, which is first hydrolysed by gamma-glutamine-transpeptidase resulti...

Garlic mustard, an invasive exotic biennial herb, has been identified in the Upper Peninsula of Michigan, but is not yet widely distributed. We tested the effectiveness and impact of management tools for garlic mustard in northern hardwood forests. Six treatment types (no treatment control, hand-pull, herbicide, hand-pull/herbicide, scorch, and hand-pull/scorch) were applied within a northern h...

INTRODUCTION Tubular toxicity is one of the most important side effects of aminoglycoside antibiotics, especially gentamicin. OBJECTIVES We histopathologically studied the effect of garlic extract and metformin co-administration, in attenuation of genetamicin induced tubular toxicity in rats. MATERIALS AND METHODS In this study seventy rats were divided into seven equal groups and except gr...

BACKGROUND Very limited information exists on the ruminal degradation kinetics of nutrients in garlic stalk. The present study aimed to survey the annual yield of garlic stalk in Korea and determine its feed-nutritive value for ruminants. METHODS In Experiment 1, garlic stalk was incubated in situ in the rumen of two Hanwoo steers (360 ± 15 kg body weight) and removed after 12, 24, or 48 h to...

BACKGROUND Garlic is widely promoted as a cholesterol-lowering agent, but efficacy studies have produced conflicting results. Garlic supplements differ in bioavailability of key phytochemicals. We evaluated the effect of raw garlic and 2 commonly used garlic supplements on cholesterol concentrations in adults with moderate hypercholesterolemia. METHODS In this parallel-design trial, 192 adult...

Garlic (Allium sativum L. fam. Alliaceae) is one of the best-researched, best-selling herbal remedies and is also commonly used for treating various health problems. Garlic is widely known for its biological properties and plays an important role as an antioxidant. The purpose of this review is to gather and summarize all dermatologic-oriented in vitro and in-vivo experiments and clinical trial...

Garlic has long been used medicinally, most recently for its cardiovascular, antineoplastic, and antimicrobial properties. Sulfur compounds, including allicin, appear to be the active components in the root bulb of the garlic plant. Studies show significant but modest lipid-lowering effects and antiplatelet activity. Significant blood pressure reduction is not consistently noted. There is some ...

Garlic (Allium sativum) is well known for its beneficial effects on health and particularly for its chemopreventive potential against cancer. The present study was designed to compare the chemopreventive efficacies of several garlic powders with various levels of alliin, a precursor of active sulfur compounds. For this purpose we used the medium-term hepatocarcinogenesis protocol (resistant hep...

Sir—In their recent article, Piscitelli et al. [1] advise that " patients receiving saqui-navir as their sole protease inhibitor should avoid using garlic supplements " [1, p. 238]. In their study, healthy volunteers who received the antiretroviral drug sa-quinavir and a garlic supplement exhibited a significant decline in plasma levels of saquinavir. As one reason for the decline in systemic l...

Sir—In their recent article, Piscitelli et al. [1] advise that " patients receiving saqui-navir as their sole protease inhibitor should avoid using garlic supplements " [1, p. 238]. In their study, healthy volunteers who received the antiretroviral drug sa-quinavir and a garlic supplement exhibited a significant decline in plasma levels of saquinavir. As one reason for the decline in systemic l...