By using agar well diffusion assay, antifungal activity of aqueous extract prepared from Egyptian garlic (Allium sativum L.) was evaluated in vitro against two strains of Aspergillus flavus (OC1 and OC10) causing human ocular infection. The recorded minimum inhibitory concentration (MIC) for growth inhibition of both strains was 3.60 mg/ml. Aqueous garlic extract (AGE) was used in successive in...

Allium sativum is an edible garllic known for its nutritional & bio-medicinal properties. The methanolic extract of stivum phytochemical screening performed analysis reveals that the extracts were rich source phytoconstituents containing Alkaloids, Carcogydrate, Glycosides, Protien, Flavanoids, Saponins, Phenolic, Steroids.Some them are responsible anti-diabetic activities. In present study...

Allium sativum L. belongs to a member of the onion family (Alliaceae) and has been used for both culinary and medical purpose. We cloned 4-coumarate:CoA ligase (4CL) from Allium sativum. 4-Coumarate:CoA ligase has an important role in the biosynthesis of plant secondary metabolites at the divergence point from general phenylpropanoid metabolism to several major branch pathways. Its deduced amin...

Context: In case of diabetes, persistent and chronic hyperglycaemia may generate free radicals and reactive oxygen species (ROS), which trigger an oxidative stress. Garlic (Allium sativum) is a rich source of bioactive compounds and is used in folk medicine for the treatment of various diseases, including diabetes. Besides, α-tocopherol and magnesium have been shown to possess antioxidative pro...

Worldly data show the increasing incidence of Mycobacterium tuberculosis (MTB) and particularly of multi-drug resistant tuberculosis (MDR-TB). In developing countries, TB control programmes are overwhelmed by the complexity of treating MDR-TB infected people, as current tools and therapies are inadequate. MDR-TB could become the main form of TB. Risk factors that make South Africa into one of t...

in the present study we aimed to evaluate the effects of methanolic extracts of the bulbs of garlic (allium sativum l., alliaceae) and persian shallot (allium ascalonicum l., alliaceae ) and leaves of sage (salvia officinalis l., lamiaceae ), ase, aae and soe respectively, on the antioxidant enzymes such as superoxide dismutase (sod), glutathione peroxidase (gpx) and catalase (cat) activities an...

To understand selenium (Se) circulation in the biosphere, the metabolism of organic Se, in particular, Se metabolites, in animals and plants should be elucidated. In this study, garlic, Allium sativum, a well-known Se accumulator with high Se metabolic ability, was hydroponically cultivated and then exposed to trimethylselenonium ion (TMSe), a urinary metabolite. Thereafter, the Se concentratio...

Results Thirty-two studies met the inclusion criteria. Clinical studies were divided into three categories: survey studies (n=11), safety studies (n= 8), and efficacy studies (n= 13). Six studies were randomized controlled trials. The most common herbs studied were St. John’s wort (Hypericum perforatum L.) (n=3), garlic (Allium sativum L.) extract (n=2), and senna (Cassia senna L.) (n=2). Studi...

Evaluation of Anticancer Effect Ginger (Zingiber officinale) and Garlic (Allium sativum) Extracts on Breast Cancer in BALB/c Mice

The sulfurous acid ester, trans-sulfurous acid allyl ester 3-allylsulfanyl-allyl ester 8, along with two known thiosulfinates was isolated from the aqueous ethanol extract of garlic (Allium sativum). The chemical structure of 8 was determined on the basis of spectroscopic data including high resolution mass and two-dimensional NMR techniques. All of these compounds induced methemoglobin formati...