The leaves of Ocimum gratissimum Linn. (Labiatae) have been used in Ayurvedic medicine since ancient times for the treatment of male sexual disorders. The present study investigated the effect ethanolic extract of ram tulsi on general mating behaviour, libido, potency along with its likely gastric ulceration and adverse effects on sexually normal male albino mice. The suspension of the extract ...

Duodenitis and gastric metaplasia, which is often colonised by Helicobacter pylori (H pylori), are increasingly recognised for their importance in the pathogenesis of duodenal ulcers. The situation is not clear in patients receiving non-steroidal anti-inflammatory drugs (NSAIDs), who have a higher risk of peptic ulceration. The aim of this study was to identify the duodenal histological abnorma...

Carbenoxolone, being a pentacyclic triterpene, is a drug which has a steroid-like structure, and despite anitiinflammatory and mineralocorticoid-like effects resembling those of steroid has shown considerable success in producing healing of gastric ulceration (Doll, Hill, Hutton, and Underwood, 1962; Horwich and Galloway, 1965). The mode of action of carbenoxolone is not yet understood. The dru...

Gastric ulceration is a prevalent condition of racehorses. A number of models of gastric ulceration have been described, but none mimic the conditions of a horse in training. The objectives of this study were to determine whether gastric ulcers could be induced and maintained in a group of horses in simulated race training. In addition, serum cortisol was measured on a weekly basis to investiga...

background: upper gastrointestinal (gi) bleeding remains a problem in critically ill-newborns. the use of h 2 blockers, by maintaining gastric ph ³ 4, reduces the risk of stress-ulceration and gastric hemorrhage. this study therefore, has evaluated the effects of short-term prophylactic‎ ranitidine in controlling gastric ph and prevention of gi bleeding in neonates.   methods: this randomized c...

AIM To explore the roles of nitric oxide synthase (NOS), heme oxygenase (HO) and cyclooxygenase (COX) in gastric ulceration and to investigate the relationships of the expression and activities of these enzymes at different stages of gastric ulceration. METHODS Gastric ulcers (kissing ulcers) were induced by luminal application of acetic acid. Gastric tissue samples were obtained from the ulc...

background: there is extensive variety of chemical compounds with antiulcer activity, which are isolated from medicinal plants. matricaria chamomilla or matricaria recutita or german chamomile, also spelled chamomile (mc), is one of the most widely used medicinal plants. in the present study, the extract of mc flowers was evaluated for antiulcerogenic activity and acute toxicity profile.   meth...

This paper reports a follow-up of 91 healthy men who had a histamine gastric function test performed 28 years ago and relates the original gastric function test to the subsequent development of duodenal ulceration.

The mechanism of acute gastric ulceration in rats with obstructive jaundice was investigated in terms of the changes in the gastric mucosal blood flow, and the effect of vagotomy on ulceration was examined. 188 Sprague-Dawley rats weighing about 250 g were prepared and divided into 4 groups as follows; control group (sham operation), jaundiced group (ligation of the bile duct), vagotomized grou...

Background:Upper gastrointestinal (GI) bleeding remains a problem in critically ill-newborns. The use of H2 blockers, by maintaining gastric pH ³ 4, reduces the risk of stress-ulceration and gastric hemorrhage. This study therefore, has evaluated the effects of short-term prophylactic‎ ranitidine in controlling gastric pH and prevention of GI bleeding in neonates. Methods: This randomized contr...