The study evaluated the ability of the alcohol extract of Butea frondosa to protect the gastro-duodenal lining from injury inflicted by acetic acid and pyloric ligation in rats. The induced gastric lesions lead to the generation of alkaline phosphatase and pepsin, which serve as important markers of gastric damage. Alcohol extract of Butea frondosa was administered in doses of 10, 100, 300 and ...

The incidence and prevalence of gastro-oesophageal reflux disease is rising. Changing dietary habits and increasing body weight can be held responsible. In several studies a close relation was found between body weight and the occurrence of reflux disease. It may be concluded that there is a definite relation between body mass index and the occurrence of reflux disease. H. pylori probably also ...

Dietary intake of probiotic bacteria has been shown to impart health effects, however, maintaining viable cells in foods and during passage of the adverse conditions in the upper gastro-intestinal tract is often a problem. The objective of this research was to develop and characterize novel food-grade phase-separated gelatin-maltodextrin (G-MD) microspheres, where the gelatin was cross-linked w...

Portal hypertension in patients with cirrhosis is the cause of many dangerous complications, such as hepatic encephalopathy, ascites, and gastro-oesophageal variceal bleeding. Gastrooesophageal variceal bleeding is the cause of more than one-third of deaths in patients with liver cirrhosis [3]. H.pylori infection has a role in some diseases as peptic ulcer [4] portal hypertensive gastropathy [5...

BACKGROUND Fructans, such as inulin, are dietary fibers which stimulate gastro-intestinal (GI) function acting as prebiotics. Lipopolysaccharide (LPS) impairs GI motility, through production of reactive oxygen species. The antioxidant activity of various fructans was tested and the protective effect of inulin on colonic smooth muscle cell (SMC) impairment, induced by exposure of human mucosa to...

BACKGROUND Nonsteroidal anti-inflammatory drugs (NSAIDs) and gastro-protective agents should be co-prescribed following a standard clinical practice guideline; however, adherence to this guideline in routine practice is unknown. This study applied an association rule model (ARM) to estimate rational NSAIDs and gastro-protective agents use in an outpatient prescriptions dataset. METHODS A data...

introduction: gp63 is a major surface protease of leishmania promastigotes that plays an important role in its virulance. as gp63 on its own can not develop an effective protection against leishmaniasis, the goal of this study was to evaluate the protective effect of gp63 conjugated with tetanus toxoid (tt) and vitamin d3 in susceptible balb/c mice against cutaneous leishmaniasis. methods: this...

Portal hypertension in patients with cirrhosis is the cause of many dangerous complications, such as hepatic encephalopathy, ascites, and gastro-oesophageal variceal bleeding. Gastrooesophageal variceal bleeding is the cause of more than one-third of deaths in patients with liver cirrhosis [3]. H.pylori infection has a role in some diseases as peptic ulcer [4] portal hypertensive gastropathy [5...