Gastroesophageal variceal hemorrhage is a lethal complication of portal hypertension. Liver cirrhosis is often the principal cause of the portal hypertensive state. Malignant tumors coexist with portal hypertension in some cases. Non-small-cell lung cancer (NSCLC) is likely to become metastatic. Liver is a frequent site of cancer metastasis, but diffuse hepatic sinusoidal metastasis is uncommon...

PURPOSE During sedated esophagogastroduodenoscopy (EGD), patients may not be able to perform inspiration, which is necessary to examine the esophagogastric junction. Therefore sedation may affect diagnosis of gastroesophageal reflux-related findings. The aim of our study was to investigate the effect of sedation on diagnosis of gastroesophageal reflux-related findings during EGD. MATERIALS AN...

Received December 19, 2007; accepted for publication April 28, 2008 Address reprint requests to Arnulf H. Hölscher, MD, FACS, FRCS: Department of General, Visceral and Cancer Surgery, University of Cologne, Kerpener Str. 62. D–50937 Köln, Germany. ©2008 The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery. All rights reserved. recent publications, early cancer accounted for ...

BACKGROUND & AIMS Over the past few decades, the incidence of adenocarcinomas of the gastroesophageal junction has rapidly increased. Barrett's esophagus is a risk factor for esophageal adenocarcinoma, but the role of intestinal metaplasia of the gastric cardia as a precursor in cardia-related cancer is controversial. The aims of the present study were to examine the prevalence of intestinal me...

BACKGROUND Patients with gastroesophageal reflux and Barrett esophagus may represent a group of patients with poorer postoperative outcomes. It has been suggested that such patients should undergo open rather than laparoscopic antireflux surgery. HYPOTHESIS The laparoscopic approach to antireflux surgery is appropriate treatment for patients with Barrett esophagus who have symptomatic gastroe...

How can cancer develop in so many different organs in so many different ways, but the outcome is similar enough to all be under the same title—cancer? There are so many causes of cancer—viruses, genetic defects, sunburn, gastroesophageal reflux, smoking, alcohol, radiation, chemicals, etc. The above variable well known etiologies of cancer could all induce a need for repair which involves alkal...

H. pylori is now a known cause of gastric and duodenal ulcers, noncardia gastric cancer and gastric MALT lymphoma. In addition, the role of this microorganism in causing or preventing a large number of other diseases has been investigated, some of which include esophageal cancer, functional dyspepsia, gastroesophageal reflux disease, asthma, cardiovascular diseases, iron deficiency anemia and i...

a 4-month-old, intact male domestic short-hair cat was presented to veterinary hospital with an acuteonset of regurgitation and respiratory distress. thoracic and abdominal radiographs identified a massconsisted of a heterogeneous mixture of soft tissue and gas densities between heart and craniodorsal part of the diaphragm that was shifted to the left. the stomach could not be seen clearly. rad...

AIM To investigate the incidence and risk factors of microscopically positive proximal margins in Chinese patients with adenocarcinoma of the gastroesophageal junction. METHODS The medical records of 483 patients, who underwent surgical treatment with curative intent for adenocarcinoma of the gastroesophageal junction in a single high-volume tertiary medical center, were reviewed. Demographic...

PURPOSE OF REVIEW The purpose of the review is to discuss key studies conducted on the intriguing relationship between Helicobacter pylori and gastroesophageal reflux disease. RECENT FINDINGS Epidemiological studies have repeatedly described a negative association between H. pylori infection and erosive esophagitis, Barrett's esophagus, and esophageal adenocarcinoma, but not between H. pylori...