In the previous study, we have found that the cordycepin which was extracted from Cordyceps mycelia produced by growing Cordyceps militaris on the dead larva of Bombyx mori silkworms showed the anti-proliferative effect toward lung cancer cells without toxicity to non-cancer cells. In this work, the cordycepin was tested for its in vitro mutagenicity and in vivo toxicity. From the Ames test and...

Preserved eggs are prone to lose water during storage, which causes the preserved shrink and have poor taste, bad flavor, reduced quality. By studying a degradable coating agent applying it eggs, we explored its effect on quality of storage. In this paper, structure performance gelatin film (GF), gelatin–bacterial cellulose (GBF), cellulose–MgO nanocomposite (GBMF) were by adding bacterial (BC)...

In this study, a system of dexamethasone sodium phosphate (DEXP)-loaded chitosan nanoparticles embedded in poly-ε-caprolacton (PCL) and gelatin electrospun nanofiber scaffold was introduced with potential therapeutic application for treatment of the nervous system. Besides anti-inflammatory properties, DEXP act through its glucocorticoid receptors, which are involved in the inhibition of astroc...

the effects of zinc oxide nanorod (zno-n) incorporation on thephysicochemical properties of tapioca starch / bovin gelatin composite film such as water absorption capacity (wаc), water solubility and permeability to water vapour (wvp) were investigated. in this search, zno-n was homogenized by sonication and added into tapioca starch / bovine gelаtin dispersions аt different concentrations (e.g...

the aim of present study was to prepare gelatin nanoparticle for drug and gene delivery applications. these nanoparticles were prepared by two-step desolvation method. the body distribution of colloidal drug delivery systems was mainly influenced by two physicochemical properties namely particle size and surface characteristics. the influence of several factors on the fabrication process includ...

Abstract Proteins are biocompatible, metabolizable, and susceptible to surface changes legend attachments for targeted distribution, therefore ideal materials nanoparticle-based drug delivery applications. The production, characterization, use of gelatin nanoparticles (GNPs) intracellular administration weakly cell-penetrating antibiotics (such as spectinomycin chloramphenicol) enhance their tr...

In this study, a system of dexamethasone sodium phosphate (DEXP)-loaded chitosan nanoparticles embedded in poly-ε-caprolacton (PCL) and gelatin electrospun nanofiber scaffold was introduced with potential therapeutic application for treatment of the nervous system. Besides anti-inflammatory properties, DEXP act through its glucocorticoid receptors, which are involved in the inhibition of astroc...

This paper provides an overview of how the surface properties of ferromagnetic nanoparticles dispersed in fluids is modified by natural and biocompatible polymers. Among common magnetic nanoparticles, magnetite (Fe3O4) and maghemite (g-Fe203) are popular candidates because of their biocompatibility. Natural polymeric coating materials are the most commonly used biocompatible magnetic nanopartic...

Ag nanoparticles (NPs) were synthesized in formic acid aqueous solutions through chemical reduction. Formic acid was used for a reducing agent of Ag precursor and solvent of gelatin. Silver acetate, silver tetrafluoroborate, silver nitrate, and silver phosphate were used as Ag precursors. Ag+ ions were reduced into Ag NPs by formic acid. The formation of Ag NPs was characterized by a UV-Vis spe...