نتایج جستجو برای: gene expression data

تعداد نتایج: 3758544  

ژورنال: کومش 2022

Introduction: Gastric cancer is a major public health issue worldwide. The factors that initiate cancer are not well understood, however aberrant expression of genes is associated with this cancer. TRIP13 plays pivotal roles in meiotic recombination, DNA repair, and cell cycle progression. An increasing body of evidence suggests that TRIP13 may possess functions other than meiosis and mitosis, ...

Background: DNA microarray is a useful technology that simultaneously assesses the expression of thousands of genes. It can be utilized for the detection of cancer types and cancer biomarkers. This study aimed to predict blood cancer using leukemia gene expression data and a robust ℓ2,p-norm sparsity-based gene selection method. Materials and Methods: In this descriptive study, the microarray ...

Aberrant DNA methylation has been reported as an important phenotype in acute myeloid leukemia. However the clinical significance of methylation changes has not been clear yet. In this study methylation Specific Melting Curve Analysis (MS-MCA) and real time PCR was used to assess the CDKN2B promoter hyper-methylation and gene expression in 59 Iranian acute myeloid leukemia (AML) patients. The i...

Most plants encounter stress such as drought and salinity that adversely affect growth, development and crop productivity. The expression of the gene glutathione-s-transferases (GST) extends throughout various protective mechanisms in plants and allows them to adapt to unfavorable environmental conditions. GSTF1 (the first phi GSTFs class) gene expression patterns in the wheat cultivars Mahuti ...

Journal: :international journal of pediatrics 0
fatemeh nazari division of physiology, department of basic sciences, faculty of veterinary medicine & institute of biotechnology, ferdowsi university of mashhad, mashhad, iran. abbas parham division of physiology, department of basic sciences, faculty of veterinary medicine & institute of biotechnology, ferdowsi university of mashhad, mashhad, iran. adham fani maleki division of physiology, department of basic sciences, faculty of veterinary medicine & institute of biotechnology, ferdowsi university of mashhad, mashhad, iran.

background bone marrow and adipose tissue are two main sources of mesenchymal stem cells (mscs). some of studies suggest that there are some differences in gene expression profile of mscs-derived from various tissues. to investigate gene expression profile by qrt-pcr, an appropriate reference gene with stable expression level should be chosen for normalizing data.  this study was designed to ev...

Journal: :molecular biology research communications 2014
ali niazi amin ramezani ali dinari

most plants encounter stress such as drought and salinity that adversely affect growth, development and crop productivity. the expression of the gene glutathione-s-transferases (gst) extends throughout various protective mechanisms in plants and allows them to adapt to unfavorable environmental conditions. gstf1 (the first phi gstfs class) gene expression patterns in the wheat cultivars mahuti ...

Aberrant DNA methylation has been reported as an important phenotype in acute myeloid leukemia. However the clinical significance of methylation changes has not been clear yet. In this study methylation Specific Melting Curve Analysis (MS-MCA) and real time PCR was used to assess the CDKN2B promoter hyper-methylation and gene expression in 59 Iranian acute myeloid leukemia (AML) patients. The i...

Journal: :physiology and pharmacology 0
saeed esmaeili-mahani department of biology, faculty of sciences, shahid bahonar university of kerman, kerman, iran zahra hajializadeh laboratory of molecular neuroscience, kerman neuroscience research center, kerman university of medical sciences, kerman, iran shima torkzadeh-mahani laboratory of molecular neuroscience, kerman neuroscience research center, kerman university of medical sciences, kerman, iran

introduction: g-proteins have an important role in the cell signaling of numerous receptors. the situation of g-proteins in health and disease and their critical role in the development of diabetic side effects is an interested scientific field. here, the changes in the expression of g-protein subunits (gαi, gαs and gβ) were evaluated in hyperglycemic situation of pc12 cells as a cellular model...

Journal: :iranian journal of public health 0
a hossein-nezhad national institute of genetic engineering and bio technology, tehran, iran gh ahangari national institute of genetic engineering and bio technology, tehran, iran b larijani endocrinology and metabolism research center, tehran university of medical sciences, iran

background: to evaluate vdr gene variation and its interaction with immune regulatory molecules in osteoporosis. methods: totally 205 pre and postmenopausal women were recruited in the study. after an overnight fast, peripheral blood was taken and centrifuged to sprat serum for measurement of serum parathyroid hormone, 25 hydroxyvitamin d, osteocal­cin and cross laps. the fok i polymorphism in ...

Journal: :iranian journal of allergy, asthma and immunology 0
leila mohammadi amirabad department of medical genetics, national institute of genetic engineering and biotechnology, tehran, iran ghasem ahangari department of medical genetics, national institute of genetic engineering and biotechnology, tehran, iran gholamreza derakhshan deilami department of lung diseases, imam khomeini hospital, tehran university of medical sciences, tehran, iran

asthma is a chronic inflammatory disorder of the airways. the stress is a factor for asthma which indicates a disorder in the function of communicational mediators of nervous and  immunological systems  such  as  neurotransmitters.  a  study  indicated  that  blood serotonin concentration increases in asthmatic patients. other study indicates that one kind of the serotonin  receptors, named 5ht...

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