نتایج جستجو برای: gene polymorphism
تعداد نتایج: 1185940 فیلتر نتایج به سال:
Abstract Background: Several single nucleotide polymorphisms have been found in CYP1A1 gene and it was reported that C allele in T/C gene polymorphism is associated with lung cancer. Current study investigates interaction between cigarette factor and C/T polymorphism in the m1 locus. Methods: Present study is a case-control and retrospective study. T/C polymorphism in 112 patients with lung...
Quantitative traits locus for milk production traits has been described on centromeric end of bovine chromosome 14. Reports name the acyl coA: diacylglycerol acyltransferase (DGAT1) gene as a potential candidate gene with dinucleotide substitution (AA to GC) in exon VIII which causes the change of lysine to alanine in amino acid (K232A).The aim of the present study was to estimate the frequency...
The primary aim of this study was to investigate the status of RANKL6-7 gene polymorphism in patients with chronic (mild, moderate, severe) and aggressive periodontitis as well as healthy controls. We examined80 patients for the RANKL6-7 polymorphisms (rs1054016 and rs9567000). Polymorphism was determinedby polymerase chain reaction (PCR) followed by direct sequencing. No statistica...
Introduction: The importance of scientific research in prevention of drug addiction is obvious. The main site of drug action is the brain. Mu receptor is the first place of drug action. In this study, the rate of mu receptor gene single nucleotide polymorphism (SNP) was compared in addicts and non-addicts. Methods: In this study AA, AG and AA polymorphism of mu receptor gene was investigated i...
Background: Perilipins are proteins at the external level of the lipid glob in adipocytes steroid-generating cells and play a central role in lipid storage and breakdown. FTO gene is associated with Type-2 diabetes (T2D) and increased fat mass. Association of Perilipin and FTO genes polymorphism with T2D was investigated. Methods: Clinical traits in a random sample of 183 Iranian men and wom...
Purpose: Estrogen as a crucial hormone during pregnancy acts by two types of receptors. Estrogen receptor alpha, expressed by estrogen receptor 1 (ESR1) gene, is more abundant and exists in all human reproductive systems. Association of ESR1 gene polymorphism has been shown in some reproductive fields such as spontaneous abortion, endometriosis-related infertility and in vitro fertili...
objective: in peripheral blood polymorphonuclear and mononuclear cells nitric oxide (no) could be synthesized by an enzyme called inducible no synthase (inos). inos gene (nos2a) is located on chromosome 17 at position 17q11.2-q12. no is released during inflammatory responses. in the present studies the frequency of nos2a gene polymorphisms and their effects on no production were investigated in...
lactoferrin is a glycoprotein with molecular weight 80 kda iron-binding bond, which is composed of 690 amino acids. in most mammalian body fluids such as sweat, semen, tears, and saliva and milk neutrophil granules there. bovine lactoferrin gene be associated with susceptibility/resistance to mastitis and even with some economically important production traits. this study was carried out to det...
normal 0 false false false en-us x-none ar-sa previous studies have inspected the associations between adiponectin (adipoq) 276g/t polymorphisms and atherosclerosis, but the results are inconclusive. the aim of this study was to explore the relationship between polymorphism +276 g > t (rs1501299) in adipoq and atherosclerosis. a widespread search was directed to identify all studies on the asso...
background: migraine is a common neurovascular disorder with multifactorial and polygenic inheritance. the aim of this study was to investigate the association of a migraine without aura and ala379val polymorphism of lipoprotein-associated phospholipase a2 (lp-pla2) gene in the iranian population. methods: in this study, 103 migraine patients and 100 healthy controls were enrolled. dna samples ...
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