نتایج جستجو برای: genomic linkage
تعداد نتایج: 165247 فیلتر نتایج به سال:
BACKGROUND Osteoporosis is a major public health problem, mainly quantified by low bone mineral density (BMD). The majority of BMD variation is determined by genetic effects. A pilot whole genome linkage scan (WGS) was previously reported in 53 white pedigrees with 630 subjects. Several genomic regions were suggested to be linked to BMD variation. OBJECTIVE To substantiate these previous find...
We constructed a genetic linkage map of Gibberella zeae (Fusarium graminearum) by crossing complementary nitrate-nonutilizing (nit) mutants of G. zeae strains R-5470 (from Japan) and Z-3639 (from Kansas). We selected 99 nitrate-utilizing (recombinant) progeny and analyzed them for amplified fragment length polymorphisms (AFLPs). We used 34 pairs of two-base selective AFLP primers and identified...
Knowledge about the genetic architecture of interspecific hybrids enables the detection of genomic regions implicated in population divergence, hence providing insight into their role as potential barriers to gene flow. We assembled genetic linkage maps for the dwarf and Normal lake whitefish species complex and their hybrids. A total of 877 AFLP loci and 30 microsatellites were positioned. The...
Sequence data are expected to increase the reliability of genomic prediction by containing causative mutations directly, especially in cases where low linkage disequilibrium between markers and causative mutations limits prediction reliability, such as across-breed prediction in dairy cattle. In practice, the causative mutations are unknown, and prediction with only variants in perfect linkage ...
Mycelium growth rate is a quantitative characteristic that exhibits continuous variation. This trait has applied interest, as growth rate is correlated with production yield and increased advantage against competitors. In this work, we studied growth rate variation in the edible basidiomycete Pleurotus ostreatus growing as monokaryotic or dikaryotic mycelium on Eger medium or on wheat straw. Ou...
Tuber quality is the subject of great interest among processing industry and consumers worldwide. Being a polygenic trait, its enhancement requires systematic understanding their genetic complexity. Molecular genetics offered valuable solutions to challenging endeavours slow gains in conventional potato breeding. With advent linkage maps, molecular markers availability next-generation sequencin...
low- temperature (lt) tolerance is an economic trait in winter wheat that determines the plants’ ability to successfully cope with below freezing temperatures. to identify the genomic regions associated with lt tolerance in hexaploid wheat, an f2:3 population was produced from crossing between winter type and tolerant parent, mirnovoskaja 808 (lt50 = -20oc), and spring type and susceptible pare...
Using DNA polymorphisms adjacent to single-copy genomic fragments derived from human chromosome 21, we initiated the construction of a linkage map of human chromosome 21. The probes were genomic EcoRI fragments pW228C, pW236B, pW231C and a portion of the superoxide dismutase gene (SOD-1). DNA polymorphisms adjacent to each of the probes were used as markers in informative families to perform cl...
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