Canine hip dysplasia (CHD) is the most common hereditary skeletal disorder in dogs. To identify common alleles associated with CHD, we genotyped 96 German Shepherd Dogs affected by mild, moderate and severe CHD and 96 breed, sex, age and birth year matched controls using the Affymetrix canine high density SNP chip. A mixed linear model analysis identified five SNPs associated with CHD scores on...

A desirable dog guide weighs 18 to 32 kg and measures 53 to 64 cm in height at the withers as an adult. Heritabilities and genetic correlations were estimated for birth weight, 42-d weight, mature weight, and mature height for 2,334 German shepherd dogs and 2,028 Labrador retrievers raised by the Seeing Eye, Inc., Morristown, NJ, from 1979 to 1997. Data included 5,006 observations for German sh...

The features of severe ischemic brain damage after strangulation by the owner of a 1-yearold German shepherd dog are described. The dog was disciplined by the owner during training by holding the dog off the ground by his choke chain collar. At first, the dog behaved normally, but he became increasingly ataxic and started circling to the left and showed reduced consciousness. The neurological e...

a 3-month-old male german shepherd dog was referred with depression, vomition, hemorrhagic diarrhea, abdominal pain, anorexia and dehydration. the affected dog did not have any history of vaccination. despite treatment, the animal died within 2 days after the onset of clinical signs. gross examination of tissues showed hemorrhages (ecchymoses) in the mucosa of the digestive tract. the liver was...

A German Shepherd Dog presented with recurrent intermandibular and intralingual swelling. Cytological and microbiological findings on fluid aspirated from the mass were consistent with an infected cyst lined by epithelium. The sinus was explored and an epithelium-lined cystic structure was extirpated from the frenulum and body of the tongue. This structure was diagnosed histologically as a derm...

Balkan Livestock Guardian Dogs (LGD) were bred to help protect sheep flocks in sparsely populated, remote mountainous areas the Balkans. The aim of this study was genomic characterization (107,403 autosomal SNPs) three LGD breeds from Balkans (Karst Shepherd, Sharplanina Dog, and Tornjak). Our analyses performed on 44 dogs representing breeds, as well 79 publicly available genotypes eight other...

BACKGROUND Pituitary dwarfism in German Shepherd Dogs is associated with autosomal recessive inheritance and a mutation in LHX3, resulting in combined pituitary hormone deficiency. Congenital dwarfism also is encountered in breeds related to German Shepherd Dogs, such as Saarloos and Czechoslovakian wolfdogs. OBJECTIVES To investigate whether Saarloos and Czechoslovakian wolfdog dwarfs have t...

Breeding practices were analysed for 32 registered dog breeds representing very small registries (120 Central Asian shepherd dogs) through to very large registries (252,521 German shepherd dogs) in Australia. The vast majority (91%) of registered kennels in Australia that were sampled did not regularly employ either close breeding or popular sire usage in their kennels and the weighted mean inb...

BREED specifications for pure-bred/pedigree dogs are laid down by the organisations that register and judge dogs, such as the Kennel Club of the UK (KCUK) and the Kennel Union of South Africa (KUSA), as well as the umbrella body the Fédération Cynologique Internationale (FCI). Reproductive isolation between breeds results because animals can only be registered as a specific breed if they have f...