Central giant cell granuloma (CGCG) is a relatively uncommon benign bony lesion of a variably aggressive nature. Thought to represent a reparative response to intrabony haemorrhage and inflammation, CGCG was once regarded as a reactive lesion. It is actually an asymptomatic lesion which becomes evident during routine radiographic examination or as a result of painless but visible expansion of t...

Giant cell granuloma is an uncommon bony lesion in the head and neck region, most commonly affecting the maxilla and mandible. Although it is a benign disease process, it can also be locally destructive. Surgery is the traditional and still the most accepted treatment for giant cell granuloma. The case described here involved the maxilla which was treated with surgical excision, followed by loc...

There are several treatment modalities to date for central giant cell granuloma including conservative treatment and surgical treatment with often planned reconstruction of the bony defect. Spontaneous bone regeneration of mandibular defects following complete resection of mandible has rarely been reported in the literature. We report a case of spontaneous bone formation after resection of a ce...

Giant cell lesions of the jaws represent distinctive clinico-pathological spectrum. They manifest as peripheral and central lesions, occurring as solitary growths to involving multiple regions of the jaw. The present report presents a unique case of giant cell lesions of the jaws, wherein a peripheral giant cell granuloma recurred exclusively as a central giant cell lesion in a young patient. T...

Peripheral Giant Cell Granuloma or so called “Giant cell epulis” is the most common oral giant cell lesion.It usually presents as a purplish-red soft tissue nodule consisting of multinucleated giant cells in a background of mononuclear stromal cells and extravasated red blood cells. This lesion probably does not represent a true neoplasm but it may be a reactive in nature which is believed to b...

background: reactive lesions of the oral cavity are non-neoplastic proliferations with very similar clinical appearance to benign neoplastic proliferation. this similarity is troublesome in the differential diagnosis. the aim of this study was to determine the frequency and distribution of oral cavity reactive lesions. materials and methods: the study was a retrospective archive review. the med...

Giant cell granuloma of the respiratory tract or Central Giant Cell Granuloma (CGCG) is considered an intraosseous, nonneoplasm tumor, responsible for less than 7% of all the mandible expansive lesions, its most common site of involvement. It affects more often the young people 75% of the cases happen to patients below 30 years of age. There is a greater predilection for females. This paper des...