introduction: central giant cell granuloma is a benign lesion but sometimes has aggressive proliferation composed of multinucleated giant cells in a background of spindle and ovoid mesenchymal cells. multifocal central giant cell granuloma of jaws is very rare and usually associated with hyperparathyroidism and some syndromes. we described an un-usual case of a 22-year-old man with idi-opathic ...

central giant cell granuloma is a benign, aggressive neoplasm composed of multinucleated giant cells that almost exclusively occurs in the jaws though extra-gnathic incidence is rare.multifocal cgcgs of the jaws are very rare and suggestive of systemic diseases such as hyperparathyroidism,an inherited syndrome such as noonan-like multiple giant cell lesion syndrome or other disorders.very few c...

Flexible biosensors exhibit great potential for the detection of various biomarkers with ability to adapt different surface textures. Here, a lab-on-a-needle biosensing platform based on ultra-flexible giant magnetoresistance (GMR) is developed. The fabricated flexible GMR sensors MR ratio 5.2% and sensitivity 0.13%/Oe in linear region, which are comparable their rigid counterparts. It found th...

Epitheloid osteosarcoma (carcinosarcoma) of the bone is a rare malignant tumor and only a few cases have been reported in the literature. In this study, we report two cases of osseous carcinosarcoma (epitheloid osteosarcoma) with immunohistochemical studies.  The morphological and immunohistochemical data in these two cases support the theory of divergent differentiation of primitive, uncommitt...

central giant cell granuloma (cgcg) is a benign proliferation of fibroblasts and multinucleated giant cells that almost exclusively occurs in the jaws. it commonly occurs in young adults showing a female predilection in the anterior mandible. multifocal cgcgs in maxillofacial region are very rare and suggestive of systemic diseases such as hyperparathyroidism, an inherited syndrome such as noon...

abstract  background: resection of the distal end of the radius is indicated in the treatment  of locally aggressive primary benign and malignant bone tumors. the aim of this study  was to evaluate the technique of osteoarticular allograft reconstruction of the distal radius after wide excision of a giant-cell tumor.  methods: we analyzed 15 patients retrospectively who had reconstruction of th...

some lesions in the oral cavity and mostly on gingiva have predominant predilection towards females, and mostly occur in the first four decades of life when changes in sex hormone levels in blood are obvious. the present study aimed to investigate the presence and distribution of estrogen and progesterone receptors in peripheral giant cell granuloma (pgcg), pyogenic granuloma (pg) and periphera...

background and objectives: giant cell tumor of bone (gct) is often regarded as a benign tumor, but its clinical course is unpredictable, has a high rate of recurrence, and even can metastases and transform to a malignant tumor. histological features of the tumor often could not predict its future biologic behavior, so it is just called ''giant cell tumor'' without indicating malignancy or benig...

Aneurysmal bone cysts (ABCs) are benign bony lesions frequently accompanied by multiple cystic lesions and aggressive bone destruction. They are relatively rare lesions, representing only 1% of bone tumors. The pathogenesis of ABCs has yet to be elucidated. In the present study, a series of 22 cases of primary and secondary ABC from patients treated in Department of Orthopedic Surgery, Kagoshim...

Chondrosarcoma (CHS) is a rare oncopathology, the third most common primary bone tumor after multiple myeloma and osteosarcoma. It accounts for about 25 % of total number sarcomas. CHS mainly affects adults occurs more often in people older than 40 years, children adolescents it less 5 all cases CHS. The sites can be any containing cartilage, but this found pelvis, femur shoulder bones, ribs. a...