Glycans of cell surface glycoproteins are involved in the regulation of cell migration, growth, and differentiation. N-acetyl-glucosaminyltransferase V (GnT-V) transfers N-acetyl-d-glucosamine to form β1,6-branched N-glycans, thus playing a crucial role in the biosynthesis of glycoproteins. This study reveals the distinct expression of GnT-V in STRO-1 and CD-146 double-positive dental pulp stem...

BACKGROUND Derivatives of D-glucosamine and D-galactosamine represent an important family of the cell surface glycan components and their fluorinated analogs found use as metabolic inhibitors of complex glycan biosynthesis, or as probes for the study of protein-carbohydrate interactions. This work is focused on the synthesis of acetylated 3-deoxy-3-fluoro, 4-deoxy-4-fluoro and 3,4-dideoxy-3,4-d...

Background: Glucosamine and chondroitin sulfate are integral components of articular cartilage and they have important role to the physiologic and mechanical properties of this tissue. Glucosamine is acting as the precursor of the disaccharide unit in glucosaminoglycans (GAGs) of Cartilage Materials and method: The use of glucosamine and chondroitin sulfate for the symptomatic treatment of os...

the purpose of this report is to present the results of analysis of actual glucosamine and/or chondroitin contents of several such products in the market place and to determine if they significantly deviate from their label claim. a total of fourteen products containing glucosamine sulfate and nine products containing chondroitin sulfate were evaluated. the amounts of glucosamine and chondroiti...

Carbohydrate-based low molecular weight gelators (LMWGs) exhibit many desirable properties making them useful in various fields including applications as drug delivery carriers. In order to further understand the structural connection gelation properties, especially influence of halide substitutions, we have designed and synthesized a series para-chlorobenzylidene acetal protected D-glucosamine...