BACKGROUND In conjunction with the growing prevalence of obesity and the older age of pregnant women gestational diabetes (GDM) is a major health problem.The aim of the study was to evaluate if a lifestyle intervention since early pregnancy is feasible in improving the glucose tolerance of women at a high-risk for GDM in Finland. METHODS A 75-g oral glucose tolerance test (OGTT) was performed...

BACKGROUND Diagnosis and follow-up of acromegaly is based on measurements of serum growth hormone (GH) concentrations during an oral glucose tolerance test (OGTT). A nadir value <1 microg/L is commonly used to define a normal response, but some authors suggest lower cutoff values. METHODS To compare the results and subsequent patient classification obtained with 3 GH assays, we obtained basal...

PURPOSE Obesity is one of the most important nutritional disorders in the world which has an obvious relationship with the incidence of metabolic diseases. Obesity prevalence has increased among children and adolescents during recent decades, leading to a rise in Type 2 diabetes mellitus (DM II) prevalence in these two age brackets. Hence, the aim of this study was to assess impaired glucose to...

Objective: To compare efficiency of glucose challenge test with oral glucose tolerance test for detection of gestational diabetes mellitus (GDM). Methods: This observational cross sectional study was conducted in The Department of Obstetrics and Gynaecology, Sharif Medical and Dental College / Sharif Medical City Hospital, from December 2012 to June, 2013. 1000 consecutive pregnant ladies were ...

OBJECTIVE To compare screen-detected diabetes prevalence and the degree of diagnostic agreement by ethnicity with the current oral glucose tolerance test (OGTT)-based and newly proposed A1C-based diagnostic criteria. RESEARCH DESIGN AND METHODS Six studies (1999-2009) from Denmark, the U.K., Australia, Greenland, Kenya, and India were tested for the probability of an A1C > or =6.5% among diabet...