نتایج جستجو برای: glutathione peroxidase gpx

تعداد نتایج: 63916  

Journal: :iranian journal of pharmaceutical research 0
seyyed ali mard physiology research center (prc), research institute for infectious diseases of digestive system and dept. of physiology, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, iran mojib azad physiology research center (prc), research institute for infectious diseases of digestive system and dept. of physiology, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, iran akram ahangarpour physiology research center (prc), research institute for infectious diseases of digestive system and dept. of physiology, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, iran

the present study aimed to evaluate the protective effect of crocin on gastric mucosal lesions caused by ischemia-reperfusion (i/r) injury in rats.forty male rats were randomly divided into sham, control (i/r injury) and three crocin-pretreated groups. to induce i/r lesions, the celiac artery was clamped for 30 min and then the clamp was removed to allow reperfusion for 3 h. pretreated-rats rec...

2016
BE Prie L Iosif I Tivig I Stoian C Giurcaneanu

Rationale:Androgenetic alopecia is not considered a life threatening disease but can have serious impacts on the patient's psychosocial life. Genetic, hormonal, and environmental factors are considered responsible for the presence of androgenetic alopecia. Recent literature reports have proved the presence of inflammation and also of oxidative stress at the level of dermal papilla cells of pati...

Journal: :Journal of limnology and freshwater fisheries research 2021

In this study, the oxidative stress effects of cadmium (Cd) toxicity depending on water temperature were investigated Gammarus pulex. The test organism individuals exposed to sublethal concentrations for 96 hours at certain rates (C1; 1/10, C2; 1/20 and C3; 1/40) LC50 values Cd each (10, 14, 18 °C). Malondialdehyde (MDA) level, glutathione peroxidase (GPx), catalase (CAT) enzyme activities temp...

Journal: :Blood 1989
S Chada C Whitney P E Newburger

We have used a cloned cDNA for the major human selenoprotein, glutathione peroxidase (GPx), to assess the mode of regulation of human GPx gene (GPX-1) expression by selenium. When the HL-60 human myeloid cell line is grown in a selenium-deficient medium, GPx enzymatic activity decreases 30-fold compared with selenium-replete cells. Upon return to a medium containing selenium in the form of sele...

2014
Amit Kunwar Christina K. Haston

Kunwar A, Haston CK. Basal levels of glutathione peroxidase correlate with onset of radiation induced lung disease in inbred mouse strains. Am J Physiol Lung Cell Mol Physiol 307: L597–L604, 2014. First published August 22, 2014; doi:10.1152/ajplung.00088.2014.— Biomarkers predicting for the radiation-induced lung responses of pneumonitis or fibrosis are largely unknown. Herein we investigated ...

Journal: :Neoplasma 2015
K Szewczyk-Golec J Tyloch J Czuczejko

UNLABELLED Prostate adenocarcinoma (PC) and benign prostate hyperplasia (BPH) are age-related diseases. The augmented oxidative stress is suggested to play an important role in the pathogenesis of both mentioned prostate disorders. In the presented study the antioxidant defense system in PC and BPH patients has been evaluated. The study was carried out on 30 PC patients (age 61±8 years) and 30 ...

2006
Jeffrey K. Yao Sherry Leonard Ravinder Reddy

Altered antioxidant status has been reported in schizophrenia. The glutathione (GSH) redox system is important for reducing oxidative stress. GSH, a radical scavenger, is converted to oxidized glutathione (GSSG) through glutathione peroxidase (GPx), and converted back to GSH by glutathione reductase (GR). Measurements of GSH, GSSG and its related enzymatic reactions are thus important for evalu...

Journal: :Cancer research 2000
S Li T Yan J Q Yang T D Oberley L W Oberley

Manganese-containing superoxide dismutase (MnSOD) is an essential primary antioxidant enzyme that converts superoxide radical to hydrogen peroxide and molecular oxygen within the mitochondrial matrix. Cytosolic glutathione peroxidase (GPX) converts hydrogen peroxide into water. MnSOD is reduced in a variety of tumor types and has been proposed to be a new kind of tumor suppressor gene, but the ...

2000
Shijun Li Tao Yan Ji-Qin Yang Terry D. Oberley Larry W. Oberley

Manganese-containing superoxide dismutase (MnSOD) is an essential primary antioxidant enzyme that converts superoxide radical to hydrogen peroxide and molecular oxygen within the mitochondrial matrix. Cytosolic glutathione peroxidase (GPX) converts hydrogen peroxide into water. MnSOD is reduced in a variety of tumor types and has been proposed to be a new kind of tumor suppressor gene, but the ...

2011
T. Tanha H. Amanlou M. Chamani Y. Ebrahimnezhad

The objectives of this study was to investigate whether consuming of protected glutamine (PG) before parturition in close up period would affect dry matter intake (DMIkg/d), blood urea nitrogen (BUNmg/dl), body condition score (BCS) and biomarkers of oxidative stress, glutathione peroxidase activity (GPX units/ml PCV) and Total Antioxidant Status (TASmmol/L). Thirty six pregnant Holstein dairy ...

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