poly (lactide-co-glycolide)/bioactive glass/hydroxyapatite (pbgha) and poly (lactide-co-glycolide)/ bioactive glass (pbg) nanocomposite coatings with bone. materials and methods: sol-gel derived 58s bioactive glass nanoparticles, 50/50 wt% poly (lactic acid)/poly (glycolic acid) and hydroxyapatite nanoparticles were used to prepare the coatings. the nanocomposite coatings were characterized by ...

A broad scope of the library squaramide organocatalysts was prepared starting from two geometric isomers (trans- and cis-(1,2-diaminocyclohexane) (DACH)) with various numbers −CH2– linkages between core aromatic group, different electron-withdrawing −CF3 groups on ring, sizes cyclic tertiary amines piperidine to pyrrolidine DACH ring. Then, ring-opening polymerizations asymmetrically substitute...

-To obtain more insight in the ring-opening polymerization of lactones, complex formation of the initiators tetraphenyltin, stannous octoate, tin tetrachloride, aluminium bromide and triisobutylaluminium (TIBA), and the monomers L(-)-lactide, D,e-lactide and glycolide was studied by i.r.-spectroscopy. When equimolar benzene or toluene solutions of initiators and monomers were combined, only com...

Angiogenesis and osteogenesis coupling processes are essential for bone regeneration, and human bone marrow stromal cells (hBMSCs) along with endothelial cells (ECs) are crucial participants. Deferoxamine (DFO), a hypoxia-mimetic agent, could activate the hypoxia-inducible factor (HIF)-1α signaling pathway and trigger angiogenic and osteogenic effects in these cells. However, the lifetime of DF...

Abstract Aqueous dispersions of gold and silver nanoparticles (NPs) stabilized with sodium citrate, as well polymeric NPs based on poly(lactide- co -glycolide) (70 : 30 mol %) poly(vinyl alcohol) have been obtained. The sizes determined by transmission electron microscopy (TEM), dynamic light scattering (DLS), analytical ultracentrifugation (AUC). It has shown that the diameter both metallic pa...

the purpose of this study was to investigate the effect of additives, poly(ethylene glycol) (peg) 1450, poloxamer 407, polyvinyl alcohol (pva) and sodium chloride in order to improve physico-chemical characteristics, encapsulation efficiency and in vitro release of bovine serum albumin, form poly(d,l-lactic-co-glycolic acid) (plga) microparticles prepared by the w/o/w solvent evaporation method...

in this study, microspheres containing estradiol valerate were prepared by solvent evaporation method using poly (glycolide-co-lactide) (plga 50:50) and poly (lactide). the effect of different process variables such as polymer type, drugpolymer ratio, stirring rate, volume of internal phase and temperature of external phase on the morphology, particle size distribution, encapsulation efficiency...