A high performance liquid chromatography method was studied for determination of 18 ?-glycyrrhetinic acid in Glycyrrhiza glabra L. (licorice) extract. The operating condition were C-18 reversed phase column (VP-ODS, (250×4.6 mm, 5 mm)) at room temperature, acetonitril/phosphoric acid (3/1) as mobile phase, at flow rate of 0.6ml/min (0-8min), 0.4ml/min (8-20min) and UV detection at 230 nm. The...

Glycyrrhetinic acid (GA) is known to inhibit glucocorticoid metabolism inhibiting 11beta-hydroxysteroid dehydrogenase (11beta-HSD). Moreover, GA administration to mice has been shown to affect the lymphoid organs through elevation of endogenous corticosterone concentration. The effect of GA administration on thymus has been demonstrated to show that considerable amounts of thymocytes undergo ap...

Abstract Water-soluble thermoresponsive polymers present either upper critical solution temperature (UCST) or lower (LCST) depending on the location of their miscibility range with water at high temperatures low temperatures. Compared LCST polymers, water-soluble UCST are still less explored until now. In this work three copolymers P(AAm-co-GAA) were synthesized by copolymerizing two acrylamide...