This article provides research to optimization of obtaining glycyrrhizic acid from dry extracts the licorice roots.Acid isolation was carried out two types extracts: 50% alcohol extract and aqueous extract.Glycyrrhizaglabra is a perennial plant, which can grow in various climatic conditions, including hot regions Kazakhstan. Stocks Kazakhstan are quite extensive estimated at several thousand to...

BACKGROUND This study aims to analyze the active pharmaceutical ingredients (APIs) of licorice (Radix Glycyrrhizae; gancao), including glycyrrhizic acid, liquiritin, isoliquiritin and total flavonoids, in multi-ingredient and multi-phase extraction by online near-infrared technology with fiber optic probes and chemometric analysis. METHODS High-performance liquid chromatography and ultraviole...

Since the first 70 years of reporting cancer chemotherapy, malignant tumors have been second most common cause death in children and adults. Currently, commonly used anti-cancer methods include surgery, radiotherapy, immunotherapy. Although these treatment could alleviate cancer, they lead to different forms side effects no particularly significant effect on prolonging patients’ life span. Glyc...

A 49-year-old female physician presented with peripheral edema, weight gain and relative hypertension caused by the consumption of licorice candy cigars containing glycyrrhizic acid (GZA) found in natural licorice extract. Although the patient's response to GZA resolved spontaneously, emergency physician awareness of the toxic effects of natural licorice extract may avert symptom progression in...

The purpose of the review is to briefly list widely used 43 drugs that can be as readily available non-toxic radioprotectors and radiomitigators in GDR relevant situations. Caffeine, acetylcysteine, ceruloplasmin, ibuprofen, acetylsalicylic acid, carnosine, cyclosporine, metformin, cholecalciferol, amifostine, artemisinin, theaflavin, succinic chlorophyllin, diltiazem, ferulic glutathione, glyc...