Nearly monodisperse hollow gold nanospheres (HGNs) with tunable interior and exterior diameters have been synthesized by sacrificial galvanic replacement of cobalt nanoparticles. It is possible to tune the peak of the surface plasmon band absorption between 550 and 820 nm by carefully controlling particle size and wall thickness. Cobalt particle size is tunable by simultaneously changing the co...

Using three different monoclonal antibodies against rat neurophysins (5), with protein A-gold as immunocytochemical marker (27), the murid hypothalamoneurohy-pophysial system was studied at the ultrastructural level. Postembedding staining was done on epoxy-embedded sections of supraoptic nuclei and posterior pituitaries. Specific immunolabeling of vasopressinergic and oxytocinergic neurosecret...

Cultured human epithelial cells (HE), grown as monolayers, acquired resistance to otherwise lethal concentrations (300 mumol/l, culture medium) of sodium aurothiomalate during five months' exposure to stepwise increased concentrations of the drug. The resistance acquired was shown by exposure to drug concentrations ranging from 25 to 300 mumol/, resulting in 100% of the resistant cells (HeMyo) ...

The number of sulphydryl groups on the erythrocyte membrane has been assessed as a function of nutritional status for two groups of patients, one receiving non-steroidal anti-inflammatory drugs (NSAIDs) and the other receiving sodium aurothiomalate (Myocrisin). The patients receiving NSAIDs had a significantly higher number of sulphydryl groups in both the glucose depleted and glucose activated...

This study was designed to probe the fabrication of unique silver and gold nano-structures engaging a self-designed chitosan-porous anodic alumina nano-composite as a template. Porous anodic alumina has been manufactured by di-step aluminum anodization in an oxalic acid electrolytic bath. The surface properties of porous anodic alumina were reinforced by chitosan neutralized in sodium hydro...

Concave gold nanoplates are obtained in hexagonal liquid crystal (LLC) made of SDS (sodium dodecyl sulfate)/glycine/HAuCl(4) aqueous solution system where glycine plays the key role. All plates are single-crystals, characterized by {111} facets, with concave centers of regular hexagonal or triangular shapes, and with better electrocatalytic activity than gold nanoplates.

The synovial membranes from 16 rheumatoid patients treated with intramuscular injections of gold sodium thiomalate were observed by light and electron microscopy with special reference to the distribution of gold particles in the tissue. 1) Light microscopic study revealed that the gold demonstrated as cytoplasmic granules by OKAMOTO’S histochemical method were contained in the synovial lining ...

Gold nanoparticles prepared by chemical reduction in sodium dodecyl sulfate (SDS) solution are size-controlled with the addition of pyrene. Micellar electrokinetic capillary chromatography (MEKC) is applied to the system to examine the size and polydispersity of gold nanoparticles and to show that pyrene has the extraordinary effect in decreasing the size and narrowing the dispersity of gold na...

OBJECTIVE To study the clinical and biochemical effects of a low starting dose for gold therapy in rheumatoid arthritis patients with a contact allergy to gold. METHODS Serum cytokines were assayed before and 24 h after the first injection of gold sodium thiomalate (GSTM). RESULTS Contact allergy to gold was found in 4 of 19 patients. Compared to gold-negative patients (starting dose: 10 mg...

Highly water-soluble mixed monolayer protected "rippled" gold nanoparticles were synthesized through a one step reaction with sodium 11-mercaptoundecanesulfonate and octanethiol ligands at various ratios.