Abstract Introduction Gorham-Scout Disease (GSD) is a rare skeletal disorder of unknown aetiology characterised by progressive osteolysis and excessive lymphovascular proliferation. Chylothorax severe life-threatening complication GSD that confers poor prognosis. Literature review reveals only one previous case successful surgical management for chylothorax secondary to GSD. Case presentation A...

Introduction Gorham-Stout Disease (GSD) is a rare disorder of bony destruction due to lymphangiomatosis, and is often triggered by hormones. One complication of GSD is the development of chylothorax, which carries a high mortality rate. Very little experience has been published to guide management in GSD during pregnancy to optimize both fetal and maternal health. Case Study A 20-year-old woman...

INTRODUCTION Gorham-Stout syndrome (GSS) is a rare but severe subtype of idiopathic osteolysis. There are no guidelines for the treatment of GSS. We analysed different diagnostic and therapeutic regimes and we describe the sucessful treatment of GSS considering individual patient factors. METHODS We diagnosed three patients with shoulder-specific GSS using clinical, radiological and histopath...

A rare disease afflicts less than 200,000 individuals, according to the National Organization for Rare Diseases (NORD) of the United States. Over 6,000 rare disorders affect approximately 1 in 10 Americans. Rare genetic bone disorders remain the major causes of disability in US patients. These rare bone disorders also represent a therapeutic challenge for clinicians, due to lack of understandin...

Sir, The article on generalized lymphangiomatosis by Putta et al.[1] was very interesting, and I would like to make a few observations regarding the article. Among the differentials mentioned by the authors – the entity of Gorham Stout syndrome is conspicuously absent – an entity which can account for almost all features with which the patient presented. Gorham Stout syndrome is a rare disease ...