Objective: To assess the clinical validity of a new grading system based on T2weighted magnetic resonance imaging (MRI) for lumbar disc degeneration Study Design: Retrospective study Overview of the Literature: Various MRI classification criteria have been widely used for evaluation of intervertebral disc pathology. However, there is still considerable controversy regarding the MRI factors that...

Abstract Glioma is the most common primary brain tumor. Molecular profiles, including IDH mutation, 1p/19q co-deletion, and MGMT promoter methylation, are highly correlated with prognosis clinical decision-making of glioma. To predict molecular profiles from rough segmentation MRI, we developed validated a gradual integration model. We proposed multi-task pseudo-3D model based on segmented mult...

PurposeAccurate glioma grading and IDH mutation status prediction are critically essential for individualized preoperative treatment decisions. This study aims to compare the diagnostic performance of magnetic resonance (MR) amide proton transfer (APT) diffusion kurtosis imaging (DKI) in prediction.MethodFifty-one patients without were retrospectively included. APT-weighted (APTw) effect DKI in...

Peritumoral edema (PTE), one of the main characteristics of malignant glioma, is a significant contributor to the morbidity and mortality from glioma, however, a recent systematic review suggested that controversy remains with regard to its prognostic value. To further determine whether PTE was a potential prognostic factor on routine pre-operative magnetic resonance imaging (MRI) for malignant...

balo's concentric multiple scleroses (ms) is a rare demyelinating disease and a variant of multiple sclerosis. we report a case with interesting misleading clinical history and typical ri findings of balo disease. a 19-year-old girl presented with fever and left hemiparesis following dental procedure 15 days ago. on physical examination fever and left limbs forces loss were noted. on ct scan a ...

BACKGROUND AND PURPOSE It has been reported that high-resolution susceptibility-weighted imaging (HR-SWI) may demonstrate brain tumor vascularity. We determined whether the degree of intratumoral susceptibility signal intensity (ITSS) on HR-SWI correlates with maximum relative cerebral blood volume (rCBVmax) and to compare its diagnostic accuracy for glioma grading with that of dynamic suscepti...

Histogram analysis of intravoxel incoherent motion and dynamic contrast-enhanced MRI with the two-compartment exchange model in glioma

Phosphatidylserine (PS), which is normally intracellular, becomes exposed on the outer surface of viable endothelial cells (ECs) of tumor vasculature. Utilizing a PS-targeting antibody, we have recently established a PS-targeted liposomal (PS-L) nanoplatform that has demonstrated to be highly tumor-selective. Because of the vascular lumen-exposed PS that is immediately accessible without a need...

BACKGROUND AND PURPOSE The purpose of this study was to determine whether qualitative and quantitative measures obtained with pulsed arterial spin-labeling (PASL) and apparent diffusion coefficients (ADC) improve glioma grading compared with conventional MR images. MATERIALS AND METHODS We prospectively performed 2 qualitative consensus reviews in 33 suspected gliomas: 1) conventional MR imag...

background: the goal of this study was to determine the reliability of tcd in evaluation of vertebrobasilar arteries in comparison with brain mra in patients suffering from acute vertebrobasilar stroke. methods: samples were patients with definite clinical diagnosis of vertebrobasilar stroke. for all patients brain mri, mra and tcd were performed during the first 48 hours of admission. basilar ...