We present a case in which a stent-graft was used to treat an aneurysm of the vertebrobasilar junction. According to our literature search, this is one of the first cases involving the intracranial placement of a stent-graft and the first case in which an aneurysm of the vertebrobasilar junction was treated in this manner. A stent-graft can be useful device for the neuroendovascular treatment o...

We report successful outcomes after endovascular placement of a stent graft in a 74- and a 77-year-old men, both of whom had malignant superior vena cava syndrome caused by squamous cell carcinoma. In each patient, successful palliation of the malignant superior vena cava syndrome was achieved by placement of a stent graft. No procedure-related complications were observed. The patients were asy...

The presented work details the computer simulation of the deployment of a stent graft in a patient-specific Abdominal Aortic Aneurysm (AAA) model, using the finite element method. The entire procedure is modeled, with the stent graft being crimped and bent according to the vessel geometry, and released in two steps. Deformations, external and internal forces during the procedure can be quantifi...

Coronary artery aneurysm (CAA) formation is a rare complication after percutaneous coronary intervention (PCI) with stent implantation. Why CAA occurs in these unusual instances is not well understood. Though cases with drug-eluting stent (DES) induced CAA have been reported before, none was reported to be associated with a titanium nitric oxide-coated bioactive stent. Herein, we describe the f...

Background: To compare the outcomes of two Thoracic Endovascular Aortic Repair (TEVAR) techniques Left Subclavian Artery (LSA) reconstruction for Stanford Type B Dissection (TBAD) patients with undesirable proximal anchoring zone. Methods: We retrospectively reviewed 57 TBAD who underwent either three dimensional (3D)-printing-assisted extracorporeal fenestration (n = 32) or conventional 25) fr...

Synthetic polymers, like methacrylate (MA) compounds, have been clinically introduced as inert coatings to locally deliver drugs that inhibit restenosis after stent. The aim of the present study was to evaluate the effects of MA coating alone on vascular smooth muscle cell (VSMC) growth in vitro. Stainless steel stents were coated with MA at the following doses: 0.3, 1.5, and 3 ml. Uncoated/bar...

We report an autopsy case of aneurysm dissection that occurred 18 months after the implantation of a Zenith stent graft. A 94-year-old woman, who had undergone an endovascular repair with postoperative reintervention, died of shock due to retroperitoneal hematoma. An autopsy indicated that the stent graft remained firmly fixed to the native aorta, whereas the dissection occurred near the proxim...

OBJECTIVE To evaluate the effect of stent based methotrexate delivery on neointimal hyperplasia. METHODS Stainless steel coronary stents and biological polymer coated (SAE) stents were randomly implanted in coronary arteries of pigs with a stent to artery ratio of 1.1:1. The pigs were killed after five days (10 stents) or four weeks (20 stents). Second, stainless steel coronary stents were di...

BACKGROUND Despite abciximab-coated stents having an inhibitory effect on coronary artery restenosis, the medium-term clinical outcome is unknown. METHODS AND RESULTS This prospective, randomized study compared the effects of the abciximab-coated stent, which was implanted in 95 patients, with those of control bare metal stents (BMS) implanted in 93 patients for de novo coronary lesions. Sten...

Atherosclerotic lesions that critically narrow the artery can necessitate an angioplasty and stent implantation. Long-term therapeutic effects, however, are limited by excessive arterial remodeling. We here employed a miniaturized nitinol-stent coated with star-shaped polyethylenglycole (star-PEG), and evaluated its bio-functionalization with RGD and CXCL1 for improving in-stent stenosis after ...