In the last two decades, Gram-positive bacteria have become the most common organisms associated with bacteremia and sepsis [1]. Moreover, clinically-significant resistance to each class of conventional antibiotics has been shown by at least one Gram-positive species, posing an additional public health challenge [2, 3]. In June 2009 in Stockholm, the 140th Nobel Symposium continued a traditiona...

Over the last several decades, a number of previously known or newly described species of gram-positive bacteria have emerged as important human pathogens, particularly in industrialized countries. These microbes have demonstrated an impressive ability to produce an array of striking infectious diseases never before seen or only infrequently encountered in the past. Despite aggressive therapeut...

nano structured materials have wide range of applications due to their interesting size-dependent chemical and physical properties compared to particles of size in the range of micrometer. copper oxide nano materials are of interest on account of their potential uses in many technological fields. in this study  cuo nanoparticles were synthesized via simple sol gel method using basic cuso4 as we...

background: serum procalcitonin (pct) levels differ in patients with bacterial or fungal infections and are significantly elevated in patients with gram-negative bacteremia. we evaluated the diagnostic accuracy of different inflammatory markers to discriminate sepsis caused by different pathogens. materials and methods: we included 328 episodes of bacteremia from 292 patients with sepsis and 31...

| Most bacterial pathogens have long filamentous structures known as pili or fimbriae extending from their surface. These structures are often involved in the initial adhesion of the bacteria to host tissues during colonization. In Gram-negative bacteria, pili are typically formed by non-covalent interactions between pilin subunits. By contrast, the recently discovered pili in Gram-positive pat...