Granular cell tumors are uncommon soft tissue neoplasm of nerve sheath origin, which are predominately benign. Granular cells can be found at any site in the body including the tongue, skin, subcutaneous tissue, breast, gastrointestinal, and urogenital systems. However, granular cell tumors have only been rarely described in the chest wall. Here we report a case of a granular cell tumor that oc...

317 degeneration to loss of Purkinje cells. In the Purkinje cell layer where neurons were lost, there were empty baskets. Degenerate Purkinje cells were accompanied by axonal torpedoes in the granular layer. The empty baskets indicate Purkinje cell loss normally de~eloped,~ while axonal torpedoes are a nonspecific sign of Purkinje cell degeneration and not a consequence of developmental f a i l...

We report on a case of extraluminal tracheal granular-cell tumor which was interpreted as a Hurthle-cell neoplasm of the thyroid on fine-needle aspirate. Review of the literature reveals only one other such case. The patient was a 35-yr-old female who presented with an enlarged thyroid. Aspiration cytology revealed a syncytium of cells with abundant granular cytoplasm interpreted as a thyroid f...

Malignant granular cell tumor is a rare malignant soft tissue neoplasm that occurs at various sites [1-18] and accounts for 1–2% of granular cell tumors [1]. Granular cell tumors are generally divided into 3 categories according to the diagnostic criteria proposed by Fanburg-Smith et al. [1], although these criteria for malignancy are still debated among pathologists. Malignant granular cell tu...

BACKGROUND Granular cell tumors are neoplasms of Schwann cell origin. They typically arise in the head and neck of adults, with the tongue being the most common location; granular cell tumors of male genitalia are exceedingly rare. We identified only eight prior cases of scrotal granular cell tumor in the literature, and only one was in a child. Herein, we report a second case of childhood scro...